Effectiveness of Tai Chi Training on Metabolic Syndrome
1 other identifier
interventional
543
1 country
2
Brief Summary
Metabolic syndrome (MetS) is a serious public health problem in Hong Kong and worldwide. Older adults, the age group with the highest prevalence of MetS, may prefer specific exercise modalities that are suitable for their regular participation to manage MetS. This project aims to evaluate the effectiveness of Tai Chi, a very suitable exercise for older adults, to alleviate MetS in older population
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Feb 2016
Typical duration for not_applicable
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2016
CompletedFirst Submitted
Initial submission to the registry
April 5, 2017
CompletedFirst Posted
Study publicly available on registry
April 11, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
February 1, 2019
CompletedSeptember 30, 2020
September 1, 2020
2.2 years
April 5, 2017
September 28, 2020
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Waist circumference
Waist circumference will be measured midway between the lowest rib and the superior border of the iliac crest using an inelastic measuring tape on the bare skin to the nearest 0.1 cm. Measurement will be performed at the end of normal expiration.
Immediately after completion of the 12-week intervention
Waist circumference
Waist circumference will be measured midway between the lowest rib and the superior border of the iliac crest using an inelastic measuring tape on the bare skin to the nearest 0.1 cm. Measurement will be performed at the end of normal expiration.
6 months after the completion of intervention
Secondary Outcomes (8)
Remission of central obesity
Immediately after completion of the 12-week intervention and 6 months after the completion of intervention
Blood triglyceride
Immediately after completion of the 12-week intervention and 6 months after the completion of intervention
High density lipoprotein-cholesterol
Immediately after completion of the 12-week intervention and 6 months after the completion of intervention
Fasting blood glucose
Immediately after completion of the 12-week intervention and 6 months after the completion of intervention
Systolic blood pressure
Immediately after completion of the 12-week intervention and 6 months after the completion of intervention
- +3 more secondary outcomes
Study Arms (3)
Passive Control
NO INTERVENTIONSubjects in this group will not receive any intervention.
Conventional Exercise
PLACEBO COMPARATORSubjects in this group will receive three 1-hour conventional exercise training sections per week for 12 weeks
Tai Chi
ACTIVE COMPARATORSubjects in this group will receive three 1-hour tai chi training sections per week for 12 weeks
Interventions
Subjects in this group will receive three 1-hour conventional exercise training sections per week for 12 weeks
Subjects in this group will receive three 1-hour tai chi training sections per week for 12 weeks
Eligibility Criteria
You may qualify if:
- Ethnic Chinese
- Abdominal Obese: Meeting the defined criteria of International Diabetes Federation (IDF) and National Cholesterol Education Program (NCEP) for abdominal obesity using Asian-specific cut off (waist circumference ≥ 90 cm for male; ≥ 80 cm for female)
You may not qualify if:
- Regularly practice moderate-intensity exercise or tai chi (\>3 times a week of \>30-min/ session)
- Serious medical and somatic condition that prevent participation in generic fitness/Tai Chi exercise
- Serious chronic diseases known to affect mobility (eg. Neurological diseases, musculoskeletal disorder and autoimmune diseases)
- Under treatment for serious chronic diseases (eg. Cancer treatment)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Angus Yulead
Study Sites (2)
The Hong Kong Polytechnic University
Hong Kong, 852, Hong Kong
The University of Hong Kong
Hong Kong, 852, Hong Kong
Related Publications (1)
Siu PM, Yu AP, Chin EC, Yu DS, Hui SS, Woo J, Fong DY, Wei GX, Irwin MR. Effects of Tai Chi or Conventional Exercise on Central Obesity in Middle-Aged and Older Adults : A Three-Group Randomized Controlled Trial. Ann Intern Med. 2021 Aug;174(8):1050-1057. doi: 10.7326/M20-7014. Epub 2021 Jun 1.
PMID: 34058100DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Parco MF Siu, PhD
The University of Hong Kong
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Research Assistant
Study Record Dates
First Submitted
April 5, 2017
First Posted
April 11, 2017
Study Start
February 1, 2016
Primary Completion
May 1, 2018
Study Completion
February 1, 2019
Last Updated
September 30, 2020
Record last verified: 2020-09