NCT03982017

Brief Summary

This is a patient-centered comparative effectiveness feasibility pilot designed to examine an intervention to increase heart failure self-care and symptom recognition. The investigators will randomize 100 participants to receive either usual care at the time of discharge after heart failure admission or a smartphone application that enhances self-care.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
32

participants targeted

Target at P25-P50 for not_applicable heart-failure

Timeline
Completed

Started Jul 2019

Shorter than P25 for not_applicable heart-failure

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 7, 2019

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 11, 2019

Completed
1 month until next milestone

Study Start

First participant enrolled

July 12, 2019

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 30, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 30, 2020

Completed
Last Updated

August 12, 2021

Status Verified

August 1, 2021

Enrollment Period

1.1 years

First QC Date

June 7, 2019

Last Update Submit

August 4, 2021

Conditions

Keywords

readmissionquality of lifeself-care

Outcome Measures

Primary Outcomes (5)

  • Percent of participants readmitted within 30 days

    30-day readmission rate as determined by participant report or medical record query

    30 days post index discharge

  • Percent of participants readmitted within 90 days

    90-day readmission rate as determined by participant report or medical record query

    90 days post index discharge

  • Time to readmission

    time to readmission

    from the date of enrollment until the date of first documented admission or date of death from any cause, whichever comes first, assessed up to 90 days

  • Kansas City Cardiomyopathy Questionnaire at 30 days post enrollment

    Quality of life, subjective level of function

    30 days post index discharge

  • Kansas City Cardiomyopathy Questionnaire at 90 days post enrollment

    Quality of life, subjective level of function

    90 days post index discharge

Study Arms (2)

Usual care

ACTIVE COMPARATOR

Consists of routine care at the time of hospital discharge, to be provided at the discretion of the clinicians caring for the participant.

Other: Usual care

Application

EXPERIMENTAL

Participants will be provided a special link to navigate to the online content and resources.

Other: Mobile Health Technology Platform

Interventions

When the participant navigates to the program, s/he will follow the directions on how to use the program, sign the terms of agreement, put in a password and begin the welcome page. The participant will receive daily prompts to complete brief questionnaires and review specialized content.

Also known as: Smartphone Program
Application

Routine care at the time of hospital discharge, to be provided at the discretion of the clinicians caring for the participant.

Usual care

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Inpatient admission for acute decompensated heart failure
  • Left ventricular systolic or diastolic heart failure
  • Owns a smartphone with a data plan

You may not qualify if:

  • Hospice or life expectancy less than 6 months
  • Palliative inotrope use
  • Heart transplant listed, or status post transplant
  • Ventricular assist devise present, or awaiting placement
  • Not being discharged to home
  • Unable to provide consent or comply with the intervention
  • Current enrollment in a remote monitoring/ telehealth program

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Pittsburgh

Pittsburgh, Pennsylvania, 15213, United States

Location

Related Publications (1)

  • Johnson AE, Routh S, Taylor CN, Leopold M, Beatty K, McNamara DM, Davis EM. Developing and Implementing an mHealth Heart Failure Self-care Program to Reduce Readmissions: Randomized Controlled Trial. JMIR Cardio. 2022 Mar 21;6(1):e33286. doi: 10.2196/33286.

MeSH Terms

Conditions

Heart Failure

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Study Officials

  • Amber E Johnson, MD

    University of Pittsburgh

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

June 7, 2019

First Posted

June 11, 2019

Study Start

July 12, 2019

Primary Completion

July 30, 2020

Study Completion

July 30, 2020

Last Updated

August 12, 2021

Record last verified: 2021-08

Data Sharing

IPD Sharing
Will not share

Locations