NCT03950661

Brief Summary

This research hypothesizes that moderate physical activity in a "green environment" (e.g. a forest preserve path) has increased benefits on psychological measures (stress, anxiety, mood, depression, attention) and on physiological measures (Heart Rate Variability, Blood Glucose, Salivary Cortisol) when directly compared to activity in a "gray environment" (urban or suburban sidewalks). The study design is a randomized crossover design in which each subject is assigned randomly to a group which determines the order in which participants will walk in each location. Subjects will take three 50-minute walks per location in one week, with half of the subjects taking the urban walks first as per group assignment. Control data are collected on days when participants do not walk. Physiological data are taken during walks and control periods (heart rate, heart rate variation). Biomarker samples (saliva, dried blood spots) are taken on selected days. Psychological data are take before and after walks and control periods.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
82

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jun 2016

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2016

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 14, 2017

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 8, 2017

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

May 13, 2019

Completed
2 days until next milestone

First Posted

Study publicly available on registry

May 15, 2019

Completed
Last Updated

May 3, 2023

Status Verified

May 1, 2023

Enrollment Period

1.2 years

First QC Date

May 13, 2019

Last Update Submit

May 1, 2023

Conditions

Keywords

naturewalkstressGreen WalkingPhysical ActivityEnvironmentanxietymood

Outcome Measures

Primary Outcomes (4)

  • Psychological Effects - Mood

    Change in Positive and Negative Affect scale 0 = never, 4 = very often. Higher Positive Affect scores reflect better reported mood scores. Lower Negative Affect Scores reflect better mood scores. Average values based on age

    29 days

  • Psychological Effects - Anxiety

    change in STAI (STAI-TRAIT anxiety) score based on a Likert scale self reported score. Higher scores indicate a higher level of self-reported anxiety.

    29 days

  • Psychological Effects - Attention

    change in vBDS (backward digit span) score lower scores indicate a increased inability to properly recall the numbers in the test.

    29 days

  • Psychological Effects - Depression

    change in CESD score. Possible range of scores is 0 to 60, with the higher scores indicating the presence of more symptomatology. Citation: Radloff LS: The CES-D Scale: a self-report depression scale for research in the general population.

    29 days

Secondary Outcomes (4)

  • Physiological Effects - Blood Glucose

    29 days

  • Physiological Effects - Salivary Cortisol

    29 days

  • Physiological Effects - Blood

    29 days

  • Physiological Effects - Heart Rate Variation

    29 days

Study Arms (2)

Forest

EXPERIMENTAL

Each subject is exposed to a 50 minute walk in a "green location" at some point during the crossover experiment. The psychological and physiological measurements taken during these walk location weeks are compared to the measurements from the other location. In addition a 'control' day is assigned for each location (ADL).

Other: Walking

Urban

EXPERIMENTAL

Each subject is exposed to a 50 minute walk in a "gray location" at some point during the crossover experiment. The psychological and physiological measurements taken during these walk location weeks are compared to the measurements from the other location. In addition a 'control' day is assigned for each location (ADL).

Other: Walking

Interventions

WalkingOTHER
ForestUrban

Eligibility Criteria

Age18 Years - 35 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • over the age of 18
  • under the age of 35
  • no current infections / recent infections (\<2weeks)
  • PAR-Q+ scores indicative of readiness to engage in physical activity

You may not qualify if:

  • Women who are pregnant or breast-feeding
  • Inability to consent
  • Incarcerated Persons
  • non-adults

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Northwestern University

Evanston, Illinois, 60208, United States

Location

MeSH Terms

Conditions

Anxiety DisordersDepressionObesityHealth BehaviorMotor Activity

Interventions

Walking

Condition Hierarchy (Ancestors)

Mental DisordersBehavioral SymptomsBehaviorOverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

LocomotionMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological PhenomenaExerciseMotor Activity

Study Officials

  • Teresa Horton

    Northwestern University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
CROSSOVER
Model Details: Randomized cross over design. Repeated measures.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 13, 2019

First Posted

May 15, 2019

Study Start

June 1, 2016

Primary Completion

August 14, 2017

Study Completion

December 8, 2017

Last Updated

May 3, 2023

Record last verified: 2023-05

Data Sharing

IPD Sharing
Will not share

Locations