NCT03950453

Brief Summary

This study will examine the mediator/moderator variables that affect efficacy of a parent stress intervention with nutrition education (PMH+N: parenting mindfully for health) vs. Control intervention with nutrition education (CTL+N) on parent stress, parenting, health behaviors and child obesity risk. A non-randomized historical control group will also be assessed during the intervention and follow-up periods throughout to obtain outcome assessment without any interventions being provided.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
246

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2018

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 11, 2018

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

April 22, 2019

Completed
23 days until next milestone

First Posted

Study publicly available on registry

May 15, 2019

Completed
4.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2023

Completed
1.3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

October 31, 2024

Completed
Last Updated

February 15, 2024

Status Verified

February 1, 2024

Enrollment Period

4.6 years

First QC Date

April 22, 2019

Last Update Submit

February 13, 2024

Conditions

Outcome Measures

Primary Outcomes (4)

  • Parent Stress change from Pre to Post intervention

    Parent stress measured by the Perceived Stress Scale scores ranging from 0-56 with higher scores indicating more stress.

    Baseline Pre-intervention to Post intervention at 12 weeks

  • Child BMI change post intervention and at short term 6 month follow-up

    Child height will be measured with a measuring tape. For children, weight and height will be plotted on the CDC growth chart for the child's age to determine the BMI-for-age percentile scores.

    Change from Pre-intervention to post-intervention (week 12) and at 6 month short term follow up

  • Child food intake change

    Parent report of child food frequency questionnaire assessment of frequency of healthy and unhealthy food intake.

    Baseline Pre-intervention and at post-intervention (week 12)

  • Parenting Behavior Change

    Observed parenting behavior ratings for increase in positive parenting behaviors in the Toy Wait Task (TWT)

    TWT parenting behavior ratings at Baseline Pre-intervention and at post-intervention (week 12)

Secondary Outcomes (4)

  • Parent Stress change from Post intervention to follow up period over 24-months

    Post intervention at 12 weeks to follow-up timepoints at 6-, 12-, 18- and 24- month timepoints

  • Child BMI change at long term term follow-up

    Baseline compared to 12-month, 18-month and 24-month timepoint

  • Child food intake change

    Baseline Pre-intervention and at post-intervention (week 12)

  • Parenting Stress Inventory (PSI)

    PSI scores at Baseline Pre-intervention and at post-intervention (week 12) and at follow-ups months 6-, 12-, 18- and 24 month timepoints

Other Outcomes (6)

  • Parent BMI

    baseline

  • Parent BMI

    at 12 week timepoint

  • Parent BMI

    at 6 month timepoint

  • +3 more other outcomes

Study Arms (3)

Parenting Mindfully for Health Nutrition (PMH)

EXPERIMENTAL

Parenting Mindfully for Health (PMH) + nutrition and physical activity counseling to promote healthy eating and physical activity in parent and child.

Behavioral: Parenting Mindfully for Health Nutrition (PMH)

Contact Control Nutrition (C+N)

ACTIVE COMPARATOR

Contact control intervention (C) + nutrition and physical activity counseling (N).

Behavioral: Contact Control Nutrition (C+N)

Historical Control (WLC) non-randomized

OTHER

Non-randomized, historical control group with only assessments during intervention and follow-up period.

Other: Non-randomized historical control (WLC) assessment only

Interventions

PMH will include included the following components: 1. mindfulness strategies as outlined in the MBSR manual, 2. mindful parenting concepts, 3. mindful eating and awareness of family choices; 4. self and child monitoring of food intake, PA and emotional reactivity; 5. utilizing mindfulness for emotion regulation and distress tolerance, 6. behavioral strategies of goal setting and implementing increasing frequency of healthy food intake and physical activity (PA)

Parenting Mindfully for Health Nutrition (PMH)

Contact Control Group where parents engage in a quiet, relaxing, but stimulating activity and also nutrition counseling.

Contact Control Nutrition (C+N)

Non-randomized, historical control group with only assessments during intervention and follow-up period.

Also known as: assessment only group
Historical Control (WLC) non-randomized

Eligibility Criteria

Age2 Years - 5 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Family with a child between 2-5 years
  • BMI of parent ≥30kg/m2
  • Parents aged 18 yrs or older
  • High parent stress (PSS mean score ≥25)
  • Low income family as determined by HHS Poverty Guidelines

You may not qualify if:

  • Diagnosis of mental retardation, autism or other pervasive developmental disorder for child;
  • Current serious psychiatric or medical disorder requiring immediate treatment, including active alcohol or substance use disorders (confirmed by urine toxicology screening and history), psychotic illnesses, suicidal ideation, untreated diabetes, cardiovascular disease, cancers or any other active current illnesses that preclude study participation for child or parent;
  • Inadequate English proficiency to complete questionnaires.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The Yale Stress Center: Yale University

New Haven, Connecticut, 06519, United States

Location

MeSH Terms

Conditions

Pediatric Obesity

Condition Hierarchy (Ancestors)

ObesityOverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Rajita Sinha

    Yale University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Masking Details
participant and outcomes assessor
Purpose
PREVENTION
Intervention Model
PARALLEL
Model Details: cohort study
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 22, 2019

First Posted

May 15, 2019

Study Start

November 11, 2018

Primary Completion

June 30, 2023

Study Completion

October 31, 2024

Last Updated

February 15, 2024

Record last verified: 2024-02

Locations