Cross-sectional, Observational, Prospective and Analytical Study:MECHANICAL POWER DAY (MPDay)

NCT03936231 | Unknown

• 1 other identifier: 2019.040
• Study Type: observational
• Target: 2,000
• Locations: 1 country
• Sites: 1

Brief Summary

Recently the new concept of "mechanical power" has been proposed. It refers to the amount of energy per minute that is transferred to the lung by the ventilator. The generation of this form of energy would include both parameters that were previously proposed to be possible causes for lung damage and new parameters that had not been taken into account until now, such as the flow rate or the respiratory rate, without forgetting the individual characteristics of each ventilated subject. The main objective of the current study is to know the value of the mechanical power in the patient connected to mechanical ventilation, in a volume control model. This value will be calculated from electronically provided data using the simplified formula by Gattinonni et. al.

Conditions

Mechanical Ventilation Complication

Keywords

VILI; Mechanical Power; Driving Pressure; Strain; Stress

Outcome Measures

Primary Outcomes (1)

• Mechanical Power (MP) (assess the amount of energy per minute that is transferred to the lung by the ventilator)

  MP=0.098 x Vt x Fr x Pp-(Pplat-PEEP/2)

  One Day

Interventions

NO Intervention OTHER

Given the observational nature of this study, we consider that no intervention is required. Participation in concomitant studies: given the observational condition of this study, patiens that are included in other observational and/or experimental researches, can be included in the current study.

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All patients that are hospitalised in a critical care area and on mechanical ventilation on the 21st of November 2019.

You may qualify if:

• Patiens with mechanical ventilation in the critical care areas.

You may not qualify if:

• Patients with not mechanical ventilation.
• Patients with mechanical ventilation for less that 6 hours.
• Traqueostomy patients
• APRV or BiLEVEL ventilation mode.
• Noninvasive ventilation d.n selectiv
• Selective ling ventilation

Sponsors & Collaborators

• Hospital Universitario Marqués de Valdecilla: lead

Study Sites (1)

Alejandro Gonzalez-Castro

Santander, 39008, Spain

Location

Related Publications (1)

• Gonzalez-Castro A, Medina Villanueva A, Escudero-Acha P, Fajardo Campoverdi A, Gordo Vidal F, Martin-Loeches I, Rocha AR, Romero MC, Hernandez Lopez M, Ferrando C, Protti A, Modesto I Alapont V; Mechanical Power Day Group. Comprehensive study of mechanical power in controlled mechanical ventilation: Prevalence of elevated mechanical power and component analysis. Med Intensiva (Engl Ed). 2024 Mar;48(3):155-164. doi: 10.1016/j.medine.2023.11.004. Epub 2023 Nov 22.

  PMID: 37996266 DERIVED

MeSH Terms

Conditions

Sprains and Strains

Condition Hierarchy (Ancestors)

Wounds and Injuries

Study Design

• Study Type: observational
• Observational Model: CASE CROSSOVER
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Critical Care Department

Study Record Dates

• First Submitted: April 24, 2019
• First Posted: May 3, 2019
• Study Start: November 21, 2019
• Primary Completion: November 21, 2019
• Study Completion: November 21, 2019
• Last Updated: May 21, 2019

Record last verified: 2019-05

Data Sharing

• IPD Sharing: Will not share

Locations

ES (1)