P-POSSUM Score and Length of Stay

NCT03933137 | Completed

• 1 other identifier: IndonesiaUAnes034
• Study Type: observational
• Target: 225
• Locations: 1 country
• Sites: 1

Brief Summary

P-POSSUM score had a predictive power of \>80% to predict the length of stay of kidney transplant recipients

Conditions

Length of Stay

Keywords

mortality; morbidity; length of stay; kidney; transplant

Outcome Measures

Primary Outcomes (3)

• Correlation between each variable of P-POSSUM and length of stay

  Correlation between 18 variables (12 variables as physical parameters and 6 variables as operative parameters) and length of stay

  1 day before surgery until discharged from hospital, up to 30 days

• P-POSSUM score Discrimination

  P-POSSUM score ability to discriminate length of stay based on variable scores: physical parameters and operative parameters

  1 day before surgery until discharged from hospital, up to 30 days

• P-POSSUM score Calibration

  P-POSSUM score cutoff to predict length of stay based on variable scores: physical parameters and operative parameters

  1 day before surgery until discharged from hospital, up to 30 days

Secondary Outcomes (16)

• Patient's length of stay post kidney transplantation

  From post surgery until discharged from hospital, up to 30 days

• P-POSSUM score (physical parameters): Age

  1 day before surgery

• P-POSSUM score (physical parameters): Heart disease

  1 day before surgery

• P-POSSUM score (physical parameters): Lung disease

  1 day before surgery

• P-POSSUM score (physical parameters): ECG abnormality

  1 day before surgery

Study Arms (2)

Not prolonged length of stay

Living donor patients who had ≤ 6 days length of stay after laparoscopic nephrectomy procedure

Other: Portsmouth Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (P-POSSUM) score

Prolonged length of stay

Living donor patients who had \> 6 days length of stay after laparoscopic nephrectomy procedure

Other: Portsmouth Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (P-POSSUM) score

Interventions

Portsmouth Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (P-POSSUM) score OTHER

P-POSSUM score's variables are divided into physiological parameters (age, cardiac, respiratory, ECG, systolic blood pressure, pulse rate, haemoglobin, leukocyte count, urea, sodium plasma, potassium plasma, and GCS) and operative parameters (operation type, number of procedures, operative blood loss, peritoneal contamination, malignancy status, CEPOD).

Not prolonged length of stay; Prolonged length of stay

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Medical record of recipients who undewernt kidney transplant during a period between January 2015 and December 2017

You may qualify if:

• Subjects are medical record of recipients who underwent kidney transplant

You may not qualify if:

• Medical record was incomplete
• Patients who died during surgery or before the patient was discharged.

Sponsors & Collaborators

• Indonesia University: lead

Study Sites (1)

Rumah Sakit Cipto Mangunkusumo

Jakarta Pusat, DKI Jakarta, 10430, Indonesia

Location

Related Publications (10)

• Reyna-Sepulveda F, Ponce-Escobedo A, Guevara-Charles A, Escobedo-Villarreal M, Perez-Rodriguez E, Munoz-Maldonado G, Hernandez-Guedea M. Outcomes and Surgical Complications in Kidney Transplantation. Int J Organ Transplant Med. 2017;8(2):78-84. Epub 2017 May 1.

  PMID: 28828167 BACKGROUND

• Howes TE, Cook TM, Corrigan LJ, Dalton SJ, Richards SK, Peden CJ. Postoperative morbidity survey, mortality and length of stay following emergency laparotomy. Anaesthesia. 2015 Sep;70(9):1020-7. doi: 10.1111/anae.12991. Epub 2015 Apr 15.

  PMID: 25872411 BACKGROUND

• McAdams-DeMarco MA, King EA, Luo X, Haugen C, DiBrito S, Shaffer A, Kucirka LM, Desai NM, Dagher NN, Lonze BE, Montgomery RA, Walston J, Segev DL. Frailty, Length of Stay, and Mortality in Kidney Transplant Recipients: A National Registry and Prospective Cohort Study. Ann Surg. 2017 Dec;266(6):1084-1090. doi: 10.1097/SLA.0000000000002025.

  PMID: 27655240 BACKGROUND

• Khambalia HA, Moinuddin Z, Summers AM, Tavakoli A, Pararajasingam R, Campbell T, Dhanda R, Forgacs B, Augustine T, van Dellen D. A prospective cohort study of risk prediction in simultaneous pancreas and kidney transplantation. Ann R Coll Surg Engl. 2015 Sep;97(6):445-50. doi: 10.1308/rcsann.2015.0001. Epub 2015 Aug 14.

  PMID: 26274754 BACKGROUND

• Grocott MP, Levett DZ, Matejowsky C, Emberton M, Mythen MG. ASA scores in the preoperative patient: feedback to clinicians can improve data quality. J Eval Clin Pract. 2007 Apr;13(2):318-9. doi: 10.1111/j.1365-2753.2006.00736.x. No abstract available.

  PMID: 17378882 BACKGROUND

• Chen T, Wang H, Wang H, Song Y, Li X, Wang J. POSSUM and P-POSSUM as predictors of postoperative morbidity and mortality in patients undergoing hepato-biliary-pancreatic surgery: a meta-analysis. Ann Surg Oncol. 2013 Aug;20(8):2501-10. doi: 10.1245/s10434-013-2893-x. Epub 2013 Feb 23.

  PMID: 23435569 BACKGROUND

• Moonesinghe SR, Mythen MG, Das P, Rowan KM, Grocott MP. Risk stratification tools for predicting morbidity and mortality in adult patients undergoing major surgery: qualitative systematic review. Anesthesiology. 2013 Oct;119(4):959-81. doi: 10.1097/ALN.0b013e3182a4e94d.

  PMID: 24195875 BACKGROUND

• Baron DM, Hochrieser H, Posch M, Metnitz B, Rhodes A, Moreno RP, Pearse RM, Metnitz P; European Surgical Outcomes Study (EuSOS) group for Trials Groups of European Society of Intensive Care Medicine; European Society of Anaesthesiology. Preoperative anaemia is associated with poor clinical outcome in non-cardiac surgery patients. Br J Anaesth. 2014 Sep;113(3):416-23. doi: 10.1093/bja/aeu098. Epub 2014 May 14.

  PMID: 24829444 BACKGROUND

• Li S, Zhou K, Lai Y, Shen C, Wu Y, Che G. Estimated intraoperative blood loss correlates with postoperative cardiopulmonary complications and length of stay in patients undergoing video-assisted thoracoscopic lung cancer lobectomy: a retrospective cohort study. BMC Surg. 2018 May 23;18(1):29. doi: 10.1186/s12893-018-0360-0.

  PMID: 29792183 BACKGROUND

• Amer MS, Hamza SA, Wahba HMF, Barakat DB. Effects of Anemia on The Outcome in Elderly Admitted to The ICU. Indian J Med Res Pharm Sci. 2016;3(April):27-32.

  BACKGROUND

MeSH Terms

Interventions

Morbidity

Intervention Hierarchy (Ancestors)

Vital Statistics; Data Collection; Epidemiologic Methods; Investigative Techniques; Demography; Population Characteristics; Epidemiologic Measurements; Public Health; Environment and Public Health

Study Officials

• Dita Aditianingsih, M.D, PhD

  Department of Anesteshiology and Intensive Care, Cipto Mangunkusumo Hospital, Universitas Indonesia

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD, PhD, Anesthesiologist Consultant

Study Record Dates

• First Submitted: April 24, 2019
• First Posted: May 1, 2019
• Study Start: May 15, 2018
• Primary Completion: August 15, 2018
• Study Completion: October 18, 2018
• Last Updated: May 1, 2019

Record last verified: 2019-04

Locations

ID (1)