The Jordan Atrial Fibrillation Study: Baseline Risk Scores and One Year Outcome

NCT03917992 | Completed DMC

• 1 other identifier: JOAF1Y
• Study Type: observational
• Target: 2,020
• Locations: 1 country
• Sites: 8

Brief Summary

The Jordanian AF study, the first of its kind in Jordan, will evaluate patients with AF in an in-patient and out-patient settings. The morbidity and mortality associated with AF has not been studied in this region especially with the relation to the HAD BLED and CHADS VAC score.

Conditions

Atrial Fibrillation

Keywords

Atrial fibrillation

Outcome Measures

Primary Outcomes (2)

• Stroke and systemic embolization at one year

  Stroke that develops from enrollment to one year of follow up (Scale: 0= no stroke at one year, 1= stroke at one year). Systemic embolization that develops in any arterial bed other than the brain from enrollment to one year of follow up (Scale: no systemic embolization at one year =0, systemic embolization at one year=1)

  one year

• Major bleeding events at one year

  Major bleeding events from enrollment to one year of follow up including: intracranial bleeding (scale: present= 1, absent=0), hospitalization for bleeding (scale: present=1, absent=2), hemoglobin decrease more than 2 gm/dL (scale: 1=present, 2=absent), and /or transfusion (scale: 1=present, 0=absent).

  one year

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All consecutive admissions aged 18+ years with new onset or known AF Admitted to participating hospitals

You may qualify if:

• Age 18 years or above
• Admission with atrial fibrillation or clinic visit for atrial fibrillation
• Signing the consent form

You may not qualify if:

• Age less than 18 years
• Refusal of signing the censent form
• Grave systemic disease with high probability of in hospital death

Sponsors & Collaborators

• Ayman J Hammoudeh, MD, FACC: lead

Study Sites (8)

Istishari Hospital

Amman, 11184, Jordan

Location

The University of Jordan

Amman, 11942, Jordan

Location

Ep Clinics Khalidi S

Amman, Jordan

Location

Integrated Center for Cardiovascular and Electric Diseases

Amman, Jordan

Location

Jordan Hospital

Amman, Jordan

Location

Khalidi Hospital & Medical Center

Amman, Jordan

Location

Specialty Hospital

Amman, Jordan

Location

King Abdullah University Hospital

Irbid, Jordan

Location

Related Publications (6)

• Abdin B, Abuqweider E, Alhaddad I, Shabaneh R, Bader G, Bader T, Abu-Shaban M, Salah Q, Hammoudeh A. The Effect of Multimorbidity and Anticoagulation Use in Patients with Atrial Fibrillation on The One-Year Outcome: Analysis from Jordan Atrial Fibrillation (JoFIB) Study - A Prospective Cohort Study. BMJ Open. 2025 Dec 28;15(12):e102661. doi: 10.1136/bmjopen-2025-102661.

  PMID: 41461398 DERIVED

• Hammoudeh A, Badaineh Y, Tabbalat R, Ahmad A, Bahhour M, Ja'ara D, Shehadeh J, Jum'ah MA, Migdad A, Hani M, Alhaddad IA. The Intersection of Atrial Fibrillation and Coronary Artery Disease in Middle Eastern Patients. Analysis from the Jordan Atrial Fibrillation Study. Glob Heart. 2024 Mar 12;19(1):29. doi: 10.5334/gh.1312. eCollection 2024.

  PMID: 38505303 DERIVED

• Alrabadi N, Al-Nusair M, Haddad R, Alburie L, Mhaidat N, Aljarrah M, Hamoudeh A. Cardiovascular medications used for comorbid diseases in patients with atrial fibrillation. The JoFib study. Eur J Clin Pharmacol. 2024 Apr;80(4):545-552. doi: 10.1007/s00228-024-03622-8. Epub 2024 Jan 23.

  PMID: 38253701 DERIVED

• Al-Makhamreh H, Alrabadi N, Haikal L, Krishan M, Al-Badaineh N, Odeh O, Barqawi T, Nawaiseh M, Shaban A, Abdin B, Khamies L, Hammoudeh A. Paroxysmal and Non-Paroxysmal Atrial Fibrillation in Middle Eastern Patients: Clinical Features and the Use of Medications. Analysis of the Jordan Atrial Fibrillation (JoFib) Study. Int J Environ Res Public Health. 2022 May 19;19(10):6173. doi: 10.3390/ijerph19106173.

  PMID: 35627709 DERIVED

• Alhaddad Z, Hammoudeh A, Khader Y, Alhaddad IA. Demographics and Risk Profile of Elderly Middle Eastern Patients with Atrial Fibrillation: The Jordan Atrial Fibrillation (JoFib) Study. Vasc Health Risk Manag. 2022 Apr 15;18:289-295. doi: 10.2147/VHRM.S360822. eCollection 2022.

  PMID: 35449533 DERIVED

• Hammoudeh AJ, Khader Y, Kadri N, Al-Mousa E, Badaineh Y, Habahbeh L, Tabbalat R, Janabi H, Alhaddad IA. Adherence to the 2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline on the Use of Oral Anticoagulant Agents in Middle Eastern Patients with Atrial Fibrillation: The Jordan Atrial Fibrillation (JoFib) Study. Int J Vasc Med. 2021 Apr 8;2021:5515089. doi: 10.1155/2021/5515089. eCollection 2021.

  PMID: 33898065 DERIVED

MeSH Terms

Conditions

Atrial Fibrillation

Condition Hierarchy (Ancestors)

Arrhythmias, Cardiac; Heart Diseases; Cardiovascular Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Ayman Hammoudeh, MD, FACC

  Cardiology Dept, Istishari Hospital, Amman, Jordan

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: The Jordanian Comprehensive Center For Electophysiologic Heart Disease

Study Record Dates

• First Submitted: April 14, 2019
• First Posted: April 17, 2019
• Study Start: May 25, 2019
• Primary Completion: November 25, 2021
• Study Completion: November 25, 2021
• Last Updated: May 25, 2023

Record last verified: 2023-05

Locations

JO (8)