NCT04074434

Brief Summary

This is a prospective, non-randomized study to refine the Study Watch's algorithm for AF detection within both persistent and paroxysmal AF subjects. The study will also collect data from an FDA-cleared wearable ECG sensor.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
160

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Nov 2018

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 12, 2018

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 17, 2019

Completed
5 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 22, 2019

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

August 22, 2019

Completed
8 days until next milestone

First Posted

Study publicly available on registry

August 30, 2019

Completed
Last Updated

September 3, 2019

Status Verified

August 1, 2019

Enrollment Period

8 months

First QC Date

August 22, 2019

Last Update Submit

August 29, 2019

Conditions

Outcome Measures

Primary Outcomes (2)

  • Estimate of the accuracy of algorithm based PPG irregular rhythm detection in a study population with a history of paroxysmal or persistent atrial fibrillation (AF)

    Sensitivity estimate for PPG irregular rhythm detection vs. a multi-lead Holter ECG rhythm

    At least 60 minutes

  • PPG- and ECG-based continuous AF-detection algorithms on Study Watch in a free-living (home) setting by comparing the Study Watch data with an FDA-cleared wearable ECG sensor data.

    Number of AF events identified from FDA-cleared ECG Device

    14 days

Secondary Outcomes (2)

  • Estimate of the accuracy of algorithm based PPG irregular rhythm detection in a study population with a history of paroxysmal or persistent atrial fibrillation (AF)

    At least 60 minutes

  • Spontaneously-reported participant usability feedback for Study Watch and its ECG feature in a free-living (home) setting with the target AF population.

    14 days

Study Arms (1)

All Participants

Device: Study Watch

Interventions

Study Watch is a miniaturized physiological data monitoring and data collection device for continuous recording of physiological and environmental data

All Participants

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Subjects with a known history of AF (including persistent or paroxysmal AF)

You may qualify if:

  • At least 18 years old
  • Able to read and speak English
  • Able and willing to sign written Informed Consent
  • Interest in participating in the study
  • Subjects with a known history of AF (including persistent or paroxysmal AF)
  • Without significant limitation in ability to participate in the study, in the opinion of the investigator.

You may not qualify if:

  • Currently in a paced rhythm
  • Known severe allergy to nickel or metal jewelry
  • Known allergic reaction to adhesives or hydrogels or with family history of adhesive skin allergies

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

San Diego Cardiac Center

San Diego, California, 92123, United States

Location

MeSH Terms

Conditions

Atrial Fibrillation

Condition Hierarchy (Ancestors)

Arrhythmias, CardiacHeart DiseasesCardiovascular DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 22, 2019

First Posted

August 30, 2019

Study Start

November 12, 2018

Primary Completion

July 17, 2019

Study Completion

July 22, 2019

Last Updated

September 3, 2019

Record last verified: 2019-08

Locations