NCT03313167

Brief Summary

To assess the prevalence of all (prevalent and paroxysmal) undiagnosed atrial fibrillation (AF) in a Japanese population with a moderate-to-high risk of stroke

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,316

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Sep 2017

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 29, 2017

Completed
13 days until next milestone

First Submitted

Initial submission to the registry

October 12, 2017

Completed
6 days until next milestone

First Posted

Study publicly available on registry

October 18, 2017

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 23, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 23, 2019

Completed
Last Updated

August 9, 2019

Status Verified

August 1, 2019

Enrollment Period

1.6 years

First QC Date

October 12, 2017

Last Update Submit

August 7, 2019

Conditions

Outcome Measures

Primary Outcomes (2)

  • number of subjects screened with AF identified at Index Visit

    Up to 4 weeks

  • number of subjects screened with AF not identified at Index Visit

    number of subjects screened who have AF not identified at their Index Visit but subsequently found to have AF confirmed by 12-lead Electrocardiogram (ECG) during the extended monitoring period

    Up to 4 weeks from Index Visit

Secondary Outcomes (10)

  • number of subjects with ECG-confirmed AF detected by the Omron BP device

    Day 1 to Day 14

  • number of subjects with ECG-confirmed AF detected by MB or HCG-801

    Day 14 to Day 28

  • number of subjects with AF identified at Index Visit who are prescribed guideline recommended anticoagulation therapy

    24 week follow up period

  • number of subjects with AF identified at their Index Visit who are prescribed guideline recommended anticoagulation therapy and still on the prescribed anticoagulation therapy at the end of the 24-week follow-up period

    At week 24

  • number of subjects with Paroxysmal atrial fibrillation (PAF) identified during the extended monitoring period who are prescribed guideline-recommended anticoagulation therapy

    Day 1 to Day 28

  • +5 more secondary outcomes

Study Arms (1)

Atrial Fibrillation-potential Patients

individuals 65 years of age or older with moderate-to-high risk of stroke

Other: Non-interventional

Interventions

Non-interventional

Atrial Fibrillation-potential Patients

Eligibility Criteria

Age65 Years+
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Japanese population with a moderate-to high risk of stroke

You may qualify if:

  • Age ≥ 65 and one or more of the following: hypertension, prior stroke or transient ischemic attack, congestive heart failure, diabetes mellitus, and/or vascular disease

You may not qualify if:

  • Age \< 65 years, individuals with AF or a history of AF, or individuals taking anti-arrhythmic drugs

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Local Institution

Itabashi-ku, Tokyo, 173-0003, Japan

Location

Related Links

MeSH Terms

Conditions

Atrial Fibrillation

Condition Hierarchy (Ancestors)

Arrhythmias, CardiacHeart DiseasesCardiovascular DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Bristol-Myers Squibb

    Bristol-Myers Squibb

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 12, 2017

First Posted

October 18, 2017

Study Start

September 29, 2017

Primary Completion

May 23, 2019

Study Completion

May 23, 2019

Last Updated

August 9, 2019

Record last verified: 2019-08

Locations