NCT03908411

Brief Summary

Paratracheal pressure may have a role in the prevention of pulmonary aspiration. The effects of paratracheal pressure on glottic view, ease of facemask ventilation, or tracheal intubation are not studied yet. In this study, the subjects are divided into two groups (group I: paratracheal pressure applied during induction of anesthesia, group II: conventional Sellick's maneuver applied during induction of anesthesia). Investigators will assess the glottic view during direct laryngoscopy.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
140

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Sep 2019

Shorter than P25 for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 5, 2019

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 9, 2019

Completed
5 months until next milestone

Study Start

First participant enrolled

September 5, 2019

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 25, 2020

Completed
3 days until next milestone

Study Completion

Last participant's last visit for all outcomes

February 28, 2020

Completed
Last Updated

November 3, 2020

Status Verified

October 1, 2020

Enrollment Period

6 months

First QC Date

April 5, 2019

Last Update Submit

November 1, 2020

Conditions

Keywords

Paratracheal pressure

Outcome Measures

Primary Outcomes (1)

  • Cormack-Lehane grade

    Cormack-Lehane grade

    During anesthesia induction procedure

Secondary Outcomes (5)

  • POGO

    During anesthesia induction procedure

  • Difficulty of mask ventilation

    During anesthesia induction procedure

  • Inspiration pressure

    During anesthesia induction procedure

  • Tidal volume

    During anesthesia induction procedure

  • Intubation difficulty

    During anesthesia induction procedure

Study Arms (2)

Paratracheal pressure

ACTIVE COMPARATOR

Left Paratracheal pressure is applied by ultrasound transducer after confirmation of the location of the esophagus.

Procedure: Paratracheal pressure

Sellick's maneuver

ACTIVE COMPARATOR

Conventional Sellick's maneuver is applied.

Procedure: Sellick's maneuver

Interventions

Paratracheal pressure is applied by 30N force with the ultrasound transducer.

Paratracheal pressure

Conventional Sellick's maneuver is applied by 30N force

Sellick's maneuver

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adult patient undergoing elective surgery with general anesthesia

You may not qualify if:

  • A patient who does not agree to participate in this study A patient who has a history of cervical/esophageal operation A patient who has a risk of gastric regurgitation A patient who has atherosclerosis of the left carotid artery or history of stroke or angina in 3 months.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Seoul National University Hospital

Seoul, 07061, South Korea

Location

SMG - SNU Boramae Medical Center

Seoul, 07061, South Korea

Location

Related Publications (1)

  • Won D, Kim H, Chang JE, Lee JM, Min SW, Ma S, Kim C, Hwang JY, Kim TK. Effect of Paratracheal Pressure on the Glottic View During Direct Laryngoscopy: A Randomized Double-Blind, Noninferiority Trial. Anesth Analg. 2021 Aug 1;133(2):491-499. doi: 10.1213/ANE.0000000000005620.

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 5, 2019

First Posted

April 9, 2019

Study Start

September 5, 2019

Primary Completion

February 25, 2020

Study Completion

February 28, 2020

Last Updated

November 3, 2020

Record last verified: 2020-10

Locations