NCT03908151

Brief Summary

Five and ten year results of the CMK21 Hip system

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Dec 2010

Longer than P75 for all trials

Geographic Reach
1 country

2 active sites

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2010

Completed
5.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2016

Completed
25 days until next milestone

First Submitted

Initial submission to the registry

August 26, 2016

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2016

Completed
2.5 years until next milestone

First Posted

Study publicly available on registry

April 9, 2019

Completed
Last Updated

April 9, 2019

Status Verified

April 1, 2019

Enrollment Period

5.7 years

First QC Date

August 26, 2016

Last Update Submit

April 5, 2019

Conditions

Keywords

hip prosthesis

Outcome Measures

Primary Outcomes (10)

  • Implant revision rate

    Listing of implant status at 5 years to analyse the survival rate

    5 years

  • Implant revision rate

    Listing of implants status at 10 years to analyse the survival rate

    10 years

  • Device related adverse events

    Medical chart will be reviewed and device related events collected to monitor the safety

    10 years

  • Device related adverse events

    Device related adverse events will be collected to monitor the safety

    5 and 10 years

  • Radiographic assessment

    Radiolucent lines and radiosclerotic lines at both the bone cement and cement prosthesis interface

    5 and 10 Years

  • Radiographic assessment

    Position and fixation of the components

    5 and 10 Years

  • Radiographic assessment

    the occurrence of osteolysis

    5 and 10 Years

  • Radiographic assessment

    the occurrence of heterotopic bone formation

    5 and 10 Years

  • Radiographic assessment

    the occurrence of atrophy or hypertrophy

    5 and 10 Years

  • Radiographic assessment

    the occurrence of cement tears/fractures

    5 and 10 Years

Secondary Outcomes (2)

  • Harris Hip Score (HHS)

    5 and 10 years

  • EuroQoL Five Dimensions Questionnaire (EQ-5D)

    5 and 10 years

Interventions

Total hip arthroplasty

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The study population consists of all patients who received a CMK21 hip stem as part of a primary total hip arthroplasty between 2005 and 2007. This includes all diagnoses, all ages, male and female.

You may qualify if:

  • The patients enrolled in the study were already operated at the time of the screening.
  • All the patients with osteoarthritis of the hip who received CMK21 hip stem between 2005 and 2007.
  • Skeletally mature patients requiring primary total hip arthroplasty due to non-inflammatory arthritis (degenerative joint disease) such as osteoarthritis, avascular necrosis, or traumatic arthritis.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Novellas Healthcare

Asse, Belgium

Location

Associatie Orthopedie Hasselt

Hasselt, Belgium

Location

MeSH Terms

Conditions

Osteoarthritis

Condition Hierarchy (Ancestors)

ArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Study Officials

  • Beate Hanson, VP, PhD

    Vice President, Global Clinical Strategy

    STUDY CHAIR

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 26, 2016

First Posted

April 9, 2019

Study Start

December 1, 2010

Primary Completion

August 1, 2016

Study Completion

October 1, 2016

Last Updated

April 9, 2019

Record last verified: 2019-04

Data Sharing

IPD Sharing
Will not share

Locations