NCT03895918

Brief Summary

This trial studies how well a parenting skills intervention works in improving medication adherence in pediatric cancer patients. The parenting skills intervention provides support and skills training to parents who administer medicine daily to their child and may improve the childs taking of medications correctly as prescribed by the doctor. Ultimately, this may improve treatment outcomes, among children who are experiencing an illness.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
9

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2019

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 3, 2019

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

March 28, 2019

Completed
1 day until next milestone

First Posted

Study publicly available on registry

March 29, 2019

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 25, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 25, 2020

Completed
Last Updated

September 16, 2021

Status Verified

September 1, 2021

Enrollment Period

1.9 years

First QC Date

March 28, 2019

Last Update Submit

September 13, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Objective medication adherence

    Assessed using Medication Event Monitoring Systems (MEMS) track caps.The project manager will conduct reviews of each child?s medical record to obtain data on the medication dose prescribed each day and dates when the medication was held for illness or toxicity. MEMS-based adherence variables will be constructed as a percentage based upon the ratio of the number of days with MEMS cap openings (X) to the number of days the medication was prescribed (N). Will remove days when the medication was held by the prescriber from the denominator (X/N x 100).

    Up to 4 weeks post study

Secondary Outcomes (3)

  • Change in parenting stress

    Baseline up to 4 weeks post study

  • Intervention feasibility

    Up to 4 weeks post study

  • Change in parenting behaviors

    Baseline up to 4 weeks

Study Arms (3)

Delayed Group (delayed parental skills)

EXPERIMENTAL

Participants continue medication adherence monitoring over 2 weeks and then receive parental skills intervention sessions consisting of 4 integrated components: creating consistent medication routines, education in child management strategies, strategies for helping children adhere to medication, and training in specific parental behavioral techniques over 30 minutes weekly for 4 weeks.

Other: Educational ActivityProcedure: Patient MonitoringOther: Questionnaire Administration

Early Group (early parental skills)

EXPERIMENTAL

Participants continue medication adherence monitoring over 1 week and then receive parental skills intervention sessions consisting of 4 integrated components: creating consistent medication routines, education in child management strategies, strategies for helping children adhere to medication, and training in specific parental behavioral techniques over 30 minutes weekly for 4 weeks.

Other: Educational ActivityProcedure: Patient MonitoringOther: Questionnaire Administration

Late Group (late parental skills)

EXPERIMENTAL

Participants continue medication adherence monitoring over 3 weeks and then receive parental skills intervention sessions consisting of 4 integrated components: creating consistent medication routines, education in child management strategies, strategies for helping children adhere to medication, and training in specific parental behavioral techniques over 30 minutes weekly for 4 weeks.

Other: Educational ActivityProcedure: Patient MonitoringOther: Questionnaire Administration

Interventions

Undergo parenting skills intervention

Delayed Group (delayed parental skills)Early Group (early parental skills)Late Group (late parental skills)

Undergo medication adherence monitoring

Also known as: monitor
Delayed Group (delayed parental skills)Early Group (early parental skills)Late Group (late parental skills)

Ancillary studies

Delayed Group (delayed parental skills)Early Group (early parental skills)Late Group (late parental skills)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Be a parent of a child (2 to 10 years old) with any hematology or oncology diagnosis who is receiving treatment at Roswell Park Comprehensive Cancer Center. We define parents as biological parents, adoptive parents, foster parents, stepparents, and legal guardians
  • Parent must have primary medication responsibility
  • The child's treatment must include home-based daily oral medication
  • Parent must have verbal English fluency
  • Participant or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedure

You may not qualify if:

  • Be a parent of a pediatric patient with any hematology or oncology diagnosis who is receiving treatment at Roswell Park and is \< 2 or \> 10 years old
  • Parent does not have primary medication responsibility
  • Child's treatment does not include home-based daily oral medication
  • Parent does not have verbal English fluency
  • If unable to consent or a prisoner
  • Unwilling or unable to follow protocol requirements
  • Any condition which in the investigator?s opinion deems the participant an unsuitable candidate to receive study intervention

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Roswell Park Cancer Institute

Buffalo, New York, 14263, United States

Location

MeSH Terms

Conditions

Hematologic DiseasesNeoplasms

Interventions

Remote Patient Monitoring

Condition Hierarchy (Ancestors)

Hemic and Lymphatic Diseases

Intervention Hierarchy (Ancestors)

TelemedicineDelivery of Health CarePatient Care ManagementHealth Services Administration

Study Officials

  • Elizabeth Bouchard

    Roswell Park Cancer Institute

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 28, 2019

First Posted

March 29, 2019

Study Start

January 3, 2019

Primary Completion

November 25, 2020

Study Completion

November 25, 2020

Last Updated

September 16, 2021

Record last verified: 2021-09

Locations