Malignant Neoplasm
219
43
55
108
Key Insights
Highlights
Success Rate
79% trial completion
Published Results
42 trials with published results (19%)
Research Maturity
108 completed trials (49% of total)
Clinical Risk Assessment
Based on trial outcomes
High Risk
Score: 72/100
12.8%
28 terminated out of 219 trials
79.4%
-7.2% vs benchmark
4%
9 trials in Phase 3/4
39%
42 of 108 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.6%
Based on 108 completed trials
Clinical Trials (219)
Molecular Profiling in Tissue Samples From Patients With Cancer Who Are Exceptional Responders to Treatment
Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)
A Study of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01D/LIGHTBEAM-U01)
Clinical Study of MK-4884 in Participants With Advanced or Metastatic Solid Tumors (MK-4884-001)
A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)
Ketoconazole in Treating Participants With Ongoing EGFR Inhibitor-Induced Rash
A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)
A Study of Belzutifan in Adolescent Participants With Solid Tumors (MK-9999-01E/LIGHTBEAM-U01)
A Clinical Study of MK-4716 in People With Certain Solid Tumors (MK-4716-001)
Use of a Pre-Surgical Toolkit in Improving Surgical Care and Outcomes in Older Participants With Cancer
A Study to Evaluate the Safety and Efficacy of MK-3120 in Participants With Advanced Solid Tumors (MK-3120-002)
Cytotoxic T Lymphocytes in Treating Patients With Malignancies With BK and/or JC Virus
KEYMAKER-U01 Substudy 01J: A Study of Pembrolizumab Plus MK-1084 in Participants With Non-Small Cell Lung Cancer (NSCLC) With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) G12C Mutations (MK-3475-01J/KEYMAKER-U01J)
Project: Every Child for Younger Patients With Cancer
A Clinical Trial of MK-2010 With Sacituzumab Tirumotecan (Sac-TMT) in Participants With Solid Tumors (MK-2010)
Palliative Radiation Therapy in Reducing Pain in Patients With Bone Metastasis
Patient-Derived Xenografts to Reduce Cancer Health Disparities
DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers.
HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal Metastases
Pre-operative SRS or Post-operative SRS in Treating Cancer Patients With Brain Metastases