NCT03885986

Brief Summary

Benign cysts and cystic-appearing lesions in and around the knee are common and differentiation between them through the history, symptoms and clinical examination is difficult due to the presence of common findings such as pain, edema, and palpable mass. The clinical presentation depends on the location, size of the lesion and its relation with the surrounding structures.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Dec 2019

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 18, 2019

Completed
4 days until next milestone

First Posted

Study publicly available on registry

March 22, 2019

Completed
9 months until next milestone

Study Start

First participant enrolled

December 10, 2019

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 10, 2021

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 10, 2021

Completed
Last Updated

July 5, 2019

Status Verified

July 1, 2019

Enrollment Period

1.5 years

First QC Date

March 18, 2019

Last Update Submit

July 3, 2019

Conditions

Knee Cyst Popliteal (___Cm)

Outcome Measures

Primary Outcomes (1)

  • Role of ultrasound and magnetic resonance imaging in diagnosis of Benign knee cysts

    Results of ultrasound in comparison to results of magnetic resonance imaging in diagnosis of Benign knee cysts.

    within 3 hours

Interventions

UltrasoundRADIATION

role of ultrasound in comparison to magnetic resonance imaging in diagnosis of benign cystic lesions of knee

Also known as: magnetic resonance imaging

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

\- Patients in different age groups referred to Radiology department at Assiut University Hospital with clinically suspected benign cystic lesions in and around the knee.

You may qualify if:

  • \. clinically diagnosed cystic lesions in and around the knee.

You may not qualify if:

  • arthroscopy or surgical intervention to the knee joint.
  • fracture repaired by metal plates or screws.
  • claustrophobia.
  • contraindications to MRI as patients with implanted pacemaker or defibrillator, ferromagnetic aneurysm clips and metallic foreign body at the knee joint.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (6)

  • Perdikakis E, Skiadas V. MRI characteristics of cysts and "cyst-like" lesions in and around the knee: what the radiologist needs to know. Insights Imaging. 2013 Jun;4(3):257-72. doi: 10.1007/s13244-013-0240-1. Epub 2013 Mar 12.

    PMID: 23479129BACKGROUND

  • Telischak NA, Wu JS, Eisenberg RL. Cysts and cystic-appearing lesions of the knee: A pictorial essay. Indian J Radiol Imaging. 2014 Apr;24(2):182-91. doi: 10.4103/0971-3026.134413.

    PMID: 25024531BACKGROUND

  • Wu JS, Hochman MG. Soft-tissue tumors and tumorlike lesions: a systematic imaging approach. Radiology. 2009 Nov;253(2):297-316. doi: 10.1148/radiol.2532081199.

    PMID: 19864525BACKGROUND

  • Bermejo A, De Bustamante TD, Martinez A, Carrera R, Zabia E, Manjon P. MR imaging in the evaluation of cystic-appearing soft-tissue masses of the extremities. Radiographics. 2013 May;33(3):833-55. doi: 10.1148/rg.333115062.

    PMID: 23674777BACKGROUND

  • Steinbach LS, Stevens KJ. Imaging of cysts and bursae about the knee. Radiol Clin North Am. 2013 May;51(3):433-54. doi: 10.1016/j.rcl.2012.10.005. Epub 2013 Jan 12.

    PMID: 23622093BACKGROUND

  • Alessi S, Depaoli R, Canepari M, Bartolucci F, Zacchino M, Draghi F. Baker's cyst in pediatric patients: Ultrasonographic characteristics. J Ultrasound. 2012 Feb;15(1):76-81. doi: 10.1016/j.jus.2011.06.007. Epub 2011 Jul 1.

    PMID: 23396996BACKGROUND

MeSH Terms

Conditions

Popliteal Cyst

Interventions

High-Energy Shock WavesMagnetic Resonance Spectroscopy

Condition Hierarchy (Ancestors)

Synovial CystCystsNeoplasms

Intervention Hierarchy (Ancestors)

Ultrasonic WavesSoundRadiation, NonionizingRadiationPhysical PhenomenaSpectrum AnalysisChemistry Techniques, AnalyticalInvestigative Techniques

Central Study Contacts

Mostafa Thabet Hussein, Professor

CONTACT

0112-299-9878thabet.mostafa@aun.edu.eg

Abeer Hossen Ali, Lecturer

CONTACT

0100-707-8382abeeryaa@yahoo.com

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
OTHER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

March 18, 2019

First Posted

March 22, 2019

Study Start

December 10, 2019

Primary Completion

June 10, 2021

Study Completion

December 10, 2021

Last Updated

July 5, 2019

Record last verified: 2019-07

Data Sharing

IPD Sharing
Will not share