WHO Fetal Growth Charts

NCT03755024 | Unknown

• 1 other identifier: WHOFC
• Study Type: observational
• Target: 102
• Locations: 0 countries
• Sites: N/A

Brief Summary

Perinatal mortality and morbidity continue to be major global health challenges strongly associated with prematurity and reduced fetal growth, an issue of further interest given the mounting evidence that fetal growth in general is linked to degrees of risk of common noncommunicable diseases in adulthood. Ultrasound estimation of fetal weight before birth is today very widely used in clinical practice, and, while essential for the identification and management of high-risk pregnancies,the current reference ranges used worldwide are largely based on single populations from a few high-income countries and are therefore of uncertain general applicability.

Conditions

Fetal Growth Complications

Outcome Measures

Primary Outcomes (1)

• Proportion of fetuses with abnormal fetal growth diagnosed using WHO fetal charts

  correlation of fetal growth pattern with neonatal birth weight and outcome

  8 months

Study Arms (2)

normal group

fetuses with normal growth

Device: ultrasound

Growth retardation group

fetuses with retarded growth

Device: ultrasound

Interventions

ultrasound DEVICE

The compulsory ultrasound measurements to be obtained at all visits include the following biometrical parameters: * Biparietal diameter * Head circumference * Abdominal circumference * Femur length * Humerus length

Growth retardation group; normal group

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

pregnant women attending Antenatal care clinic of Women's Health Hospital, Faculty of Medicine, Assiut university.

You may qualify if:

• They have body-mass index between 18-30;
• They have a singleton pregnancy;
• Their gestational age at entry is between 8+0 to 12+6 weeks based on last menstrual period.

You may not qualify if:

• Multiple pregnancy
• Congenital fetal malformation (cardiac, cerebral, renal malformations, etc.)

Sponsors & Collaborators

• Assiut University: lead

MeSH Terms

Interventions

Ultrasonography

Intervention Hierarchy (Ancestors)

Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: November 25, 2018
• First Posted: November 27, 2018
• Study Start: January 1, 2019
• Primary Completion: January 1, 2020
• Study Completion: May 1, 2020
• Last Updated: November 27, 2018

Record last verified: 2018-11