NCT03869879

Brief Summary

Phase II of this study includes a pragmatic clinical trial which will take place at Northwest Rehabilitation Associates (NWRA) in Salem, OR to verify the efficacy of the system in a physical therapy clinic.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
300

participants targeted

Target at P75+ for not_applicable parkinson-disease

Timeline
Completed

Started Jul 2019

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 20, 2019

Completed
19 days until next milestone

First Posted

Study publicly available on registry

March 11, 2019

Completed
5 months until next milestone

Study Start

First participant enrolled

July 24, 2019

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 30, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 30, 2021

Completed
Last Updated

May 11, 2020

Status Verified

May 1, 2020

Enrollment Period

1.9 years

First QC Date

February 20, 2019

Last Update Submit

May 8, 2020

Conditions

Keywords

gaitbalancefallsmobilityfeedback

Outcome Measures

Primary Outcomes (1)

  • Activities-Specific Balance Confidence (ABC) Scale

    This questionnaire measures an individual's perception of their own balance. Individuals use a scale ranging from 0% to 100% in rating the amount of confidence they have in their balance during 16 hypothetical daily-life activities. A score of 100% would represent one being fully confident in their balance during a specific task, while a score of 0% would represent one having no confidence at all in their balance. Total score ranges from 0 to 1600.

    Collected at a participant's baseline visit and final study visit, after an average of one month

Secondary Outcomes (1)

  • Gait speed

    Collected at a participant's baseline visit and final study visit, after an average of one month

Study Arms (2)

Feedback-assisted physical therapy

ACTIVE COMPARATOR

During a visual feedback session, therapists will spend 30min per session using the Mobility Rehab system for gait training with patients. Therapists may select modality, overground walking and/or treadmill, tasks (dual task, head turns, etc. as above) as appropriate for each patient. They will additionally spend 15min on endurance, strength, and static and dynamic balance in functional tasks.

Other: Feedback-assisted physical therapy

Traditional physical therapy

PLACEBO COMPARATOR

During a regular session, patients with gait impairment will work on gait with the following tasks for 30min: weights on ankles, dual tasks, UE support, partial body weight support, speed challenges, obstacles, and head turning. Therapists may select modality, overground walking and/or treadmill, tasks (dual task, head turns, etc. as above) as appropriate for each patient. They will additionally spend 15min on endurance, strength, and static and dynamic balance in functional tasks.

Other: Traditional physical therapy

Interventions

The system uses unobtrusive, wearable, inertial sensors with real-time algorithms to provide real-time feedback on: step time asymmetry, foot clearance, arm swing, trunk lateral range, and foot strike angle during gait.

Feedback-assisted physical therapy

Therapists will treat these patients with traditional therapeutic modalities and practices.

Traditional physical therapy

Eligibility Criteria

Age60 Years - 89 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years old
  • gait disturbances requiring physical therapy

You may not qualify if:

  • unable to follow instructions (up to the practitioner's judgement)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Northwest Rehabilitation Associate

Salem, Oregon, 97302, United States

RECRUITING

Related Publications (2)

  • Silva-Batista C, Harker G, Vitorio R, Studer M, Whetten B, Lapidus J, Carlson-Kuhta P, Pearson S, VanDerwalker J, Horak FB, El-Gohary M, Mancini M. Mobility Rehab visual feedback system for gait rehabilitation in older adults. J Neuroeng Rehabil. 2023 Oct 24;20(1):144. doi: 10.1186/s12984-023-01260-2.

  • Vitorio R, El-Gohary M, Pearson S, Carlson-Kuhta P, Harker G, Horak FB, Lapidus J, Studer M, Mancini M. Effectiveness of the Mobility Rehab System for Mobility Training in Older Adults: A Pragmatic Clinical Trial. Front Neurol. 2021 Sep 6;12:680637. doi: 10.3389/fneur.2021.680637. eCollection 2021.

MeSH Terms

Conditions

Parkinson DiseaseStrokeMultiple SclerosisGait Disorders, NeurologicGait Ataxia

Condition Hierarchy (Ancestors)

Parkinsonian DisordersBasal Ganglia DiseasesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesMovement DisordersSynucleinopathiesNeurodegenerative DiseasesCerebrovascular DisordersVascular DiseasesCardiovascular DiseasesDemyelinating Autoimmune Diseases, CNSAutoimmune Diseases of the Nervous SystemDemyelinating DiseasesAutoimmune DiseasesImmune System DiseasesNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsAtaxiaDyskinesias

Study Officials

  • Martina Mancini, PhD

    Oregon Health and Science University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Martina Mancini, PhD

CONTACT

Fay Horak, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Masking Details
Directing physical therapist will assess eligibility, and randomize participants. Physical therapy aide will conduct baseline measures (questionnaires, ABC scale, and 2min walk). The four treating physical therapists are split into two groups: two therapists will provide traditional physical therapy, while the two other therapists will provide visual feedback-aided therapy for their participants. A second, blinded physical therapy aide will complete a follow-up assessment (ABC scale, 2min walk).
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Eligible participants are randomized into two groups. One group will receive standard physical therapy for their gait or balance issue while the other will receive visual feedback-aided physical therapy.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

February 20, 2019

First Posted

March 11, 2019

Study Start

July 24, 2019

Primary Completion

May 30, 2021

Study Completion

May 30, 2021

Last Updated

May 11, 2020

Record last verified: 2020-05

Data Sharing

IPD Sharing
Will share

At the conclusion of the study raw data of motor tasks will be available, within the bounds allowed by HIPAA and institutional privacy policies.

Shared Documents
STUDY PROTOCOL, SAP
Time Frame
At the conclusion of the project.
Access Criteria
Email study PI for IPD access

Locations