NCT05436067

Brief Summary

The aim of this study is to test whether when using the Vestibular Rehabilitation App older patients perform rehabilitation in a similar manner as when directly instructed by a clinician. A secondary goal is to evaluate usability and enjoyment of the app.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started May 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 23, 2022

Completed
14 days until next milestone

First Submitted

Initial submission to the registry

June 6, 2022

Completed
22 days until next milestone

First Posted

Study publicly available on registry

June 28, 2022

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 13, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 13, 2023

Completed
2.3 years until next milestone

Results Posted

Study results publicly available

April 24, 2025

Completed
Last Updated

April 24, 2025

Status Verified

March 1, 2025

Enrollment Period

8 months

First QC Date

June 6, 2022

Results QC Date

October 6, 2023

Last Update Submit

April 7, 2025

Conditions

Keywords

balancetelehealthphysical therapymobile applicationserious gamingrehabilitationvestibulardizziness

Outcome Measures

Primary Outcomes (13)

  • Perceived Usefulness

    The ease of use of information technology questionnaire is used to rate usefulness and perceived ease of use of the Vestibular Rehabilitation app. These are rated on a scale of 1-7, with 1 being the most positive response, 4 being a neutral response and 7 being the most negative response.

    Immediately after the testing

  • User Interface Satisfaction Questionnaire Outcomes

    The questionnaire for user interface satisfaction (QUIS) is used to rate the Vestibular Rehabilitation app on use of its software and screen. These are rated on a scale of 0-9, with 9 being the most positive response and 0 being the most negative response.

    Immediately after the testing

  • Use Intention, Motivation and Enjoyment

    A questionnaire on use intention, motivation, and enjoyment is used to rate the Vestibular Rehabilitation app on the use intention, motivation and enjoyment of the app. These are rated on a scale of 1-7, with 1 being the most positive response, 4 being a neutral response and 7 being the most negative response.

    Immediately after the testing

  • Change in Head Angle With the App

    The IMU sensor data collected during the exercise performance with and without the Vestibular Rehabilitation App (collected in the same lab visit on the same group of participants) were analyzed to calculate peak head angles. These were analyzed to identify differences for the conditions with and without the Vestibular Rehabilitation App.

    During the testing with the app and during the testing without the app (up to 90 minutes)

  • Change in Range of Motion With the App

    The IMU sensor data collected during the exercise performance with and without the Vestibular Rehabilitation App (collected in the same lab visit on the same group of participants) were analyzed to calculate head range of motion values. These were analyzed to identify differences for the conditions with and without the Vestibular Rehabilitation App

    During the testing with the app and during the testing without the app (up to 90 minutes)

  • Change in Head Motion Frequency With the App

    The IMU sensor data collected during the exercise performance with and without the Vestibular Rehabilitation App (collected in the same lab visit on the same group of participants) were analyzed to calculate frequency of head motion. These were analyzed to identify differences for the conditions (arms) with and without the Vestibular Rehabilitation App

    During the testing with the app and during the testing without the app (up to 90 minutes)

  • Change in Balance Outcome With the App - Weight Shift Exercise

    The IMU sensor data collected during the exercise performance with and without the Vestibular Rehabilitation App (collected in the same lab visit on the same group of participants) were analyzed to calculate range of motion in different directions during the weight shift balance exercise (in degrees). These were analyzed to identify differences for the conditions with and without the Vestibular Rehabilitation App

    During the testing with the app and during the testing without the app (up to 90 minutes)

  • Change in Head Angle With Feedback

    The IMU sensor data collected during the exercise performance with the Vestibular Rehabilitation App will be analyzed to calculate peak head angles. Averages will be calculated for time windows before and after feedback on exercise performance is given. This will be analyzed to identify differences before and after feedback has been given.

    During the testing with the app (up to 45 minutes)

  • Change in Range of Motion With Feedback

    The IMU sensor data collected during the exercise performance with the Vestibular Rehabilitation App will be analyzed to calculate range of motion values. Averages will be calculated for time windows before and after feedback on exercise performance is given. This will be analyzed to identify differences before and after feedback has been given.

    During the intervention with the app (up to 45 minutes)

  • Change in Angular Velocity With Feedback

    The IMU sensor data collected during the exercise performance with the Vestibular Rehabilitation App will be analyzed to calculate angular velocity values . Averages will be calculated for time windows before and after feedback on exercise performance is given. This will be analyzed to identify differences before and after feedback has been given.

    During the intervention with the app (up to 45 minutes)

  • Change in Balance Outcome With Feedback

    The IMU sensor data collected during the exercise performance with the Vestibular Rehabilitation App will be analyzed to calculate balance measures (jerk). Averages will be calculated for time windows before and after feedback on exercise performance is given. This will be analyzed to identify differences before and after feedback has been given.

    During the intervention with the app (up to 45 minutes)

  • Error Identification Differences

    The exercise errors that are identified by the Vestibular Rehabilitation App and those identified by the physical therapist will be compared.

    During the intervention with the app (up to 45 minutes)

  • Change in Balance Outcome With the App - Single Leg Balance

    The IMU sensor data collected during the exercise performance with and without the Vestibular Rehabilitation App (collected in the same lab visit on the same group of participants) were analyzed to calculate balance measure fluency (a non-dimensional derivative of jerk). This was analyzed to identify differences for the conditions with and without the Vestibular Rehabilitation App

    During the testing with the app and during the testing without the app (up to 90 minutes)

Secondary Outcomes (1)

  • Open Ended Feedback

    Immediately after the intervention

Study Arms (2)

Trials with Vestibular Rehabilitation App

EXPERIMENTAL

All participants underwent the same experiment. They will performed exercises with the Vestibular Rehabilitation App as well as without the App. The order was randomized. This arm describes the results of the trials where exercises were performed with the Vestibular Rehabilitation App.

Device: Vestibular rehabilitation app

Trials without Vestibular Rehabilitation App

EXPERIMENTAL

All participants underwent the same experiment. They will performed exercises with the Vestibular Rehabilitation App as well as without the App. The order was randomized. This arm describes the results of the trials where exercises were performed without the Vestibular Rehabilitation App.

Other: Traditional Physical Therapy

Interventions

Delivery of vestibular rehabilitation through an app on a tablet or other portable device. The app takes patients through their rehabilitation session that has been prescribed by a clinician. Exercises are presented in the forms of games that are controlled by head or torso motion via a motion sensor that is placed on that body part. Data on the motion of the patient are calculated from sensor data and sent over the cloud for the clinician to access remotely.

Trials with Vestibular Rehabilitation App

Delivery of vestibular rehabilitation through traditional physical therapy.

Trials without Vestibular Rehabilitation App

Eligibility Criteria

Age60 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • aged between 60 and 75
  • Presence of dizziness due to a central or peripheral vestibular disorder

You may not qualify if:

  • Presence of neurological disease such as stroke, multiple sclerosis, Parkinson's
  • History of recent lower extremity surgery or severe pain in legs

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Kansas Medical Center

Kansas City, Kansas, 66160, United States

Location

Related Publications (4)

  • DSilva LJ, Skop KM, Pickle NT, Marschner K, Zehnbauer TP, Rossi M, Roos PE. Use of Stakeholder Feedback to Develop an App for Vestibular Rehabilitation-Input From Clinicians and Healthy Older Adults. Front Neurol. 2022 Feb 24;13:836571. doi: 10.3389/fneur.2022.836571. eCollection 2022.

    PMID: 35280295BACKGROUND
  • Davis, F. D. Perceived Usefulness, Perceived Ease of Use, and User Acceptance of Information Technology. MIS Quarterly. 1989; 13(3): 319-340.

    BACKGROUND
  • Chin, J.P., Diehl, V.A., and Norman, K.L. Development of a tool measuring user satisfaction of the human-computer interface. CHI '88: Proceedings of the SIGCHI Conference on Human Factors in Computing Systems. 1988; 213-218.

    BACKGROUND
  • van Het Reve E, Silveira P, Daniel F, Casati F, de Bruin ED. Tablet-based strength-balance training to motivate and improve adherence to exercise in independently living older people: part 2 of a phase II preclinical exploratory trial. J Med Internet Res. 2014 Jun 25;16(6):e159. doi: 10.2196/jmir.3055.

    PMID: 24966165BACKGROUND

MeSH Terms

Conditions

Vestibular DiseasesDizziness

Condition Hierarchy (Ancestors)

Labyrinth DiseasesEar DiseasesOtorhinolaryngologic DiseasesSensation DisordersNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Results Point of Contact

Title
Dr. Paulien Roos
Organization
CFD Research Corporation

Study Officials

  • Paulien Roos, PhD

    CFD Research Corporation

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 6, 2022

First Posted

June 28, 2022

Study Start

May 23, 2022

Primary Completion

January 13, 2023

Study Completion

January 13, 2023

Last Updated

April 24, 2025

Results First Posted

April 24, 2025

Record last verified: 2025-03

Data Sharing

IPD Sharing
Will share

All resources developed for this project will be presented at conferences and published in the literature where possible. Whenever possible the investigators will include supplemental data (de-identified) in the online versions of their publications to most fully disseminate our results. Also, resources and de-identified data will be made available, whenever possible and appropriate, to qualified persons upon request.

Time Frame
Data will be available upon request after they have been published
Access Criteria
Upon request

Locations