Smoke Inhalation Injury in Patients Admitted to Intensive Care

NCT03834246 | Unknown DMC

• 1 other identifier: Cicit805
• Study Type: observational
• Target: 700
• Locations: 1 country
• Sites: 1

Brief Summary

Many Studies have shown that the smoke-inhalation injury is responsible for a high mortality mainly related to the systemic effects of carbon monoxide and cyanide. Respiratory lesions induced by smoke inhalation, is one of predictive factors of mortality. The aim of the study is to identify the clinical and epidemiological characteristics of smoke-inhalation injury and to identify prognostic factors among these patients .

Conditions

Smoke Inhalation Injury; Morality

Keywords

Prognostic Factors; intensive care unit

Outcome Measures

Primary Outcomes (1)

• mortality rate

  survival study for the search of prognostic factors

  20 years

Secondary Outcomes (1)

• epidemiologic characteritics

  20 years

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

We performed a retrospective study of patients admitted to a university affiliated hospital ICU between December 1997 and september 2018 following smoke -inhalation poisoning. Outcomes were survival to ICU discharge .

You may qualify if:

• Men or women over the age of 18
• Hyperbaric oxygen therapy between 1997 and 2018

You may not qualify if:

• Patients under 18 years old.
• Patient opposed to the use of his data
• Patients not treated with hyperbaric oxygen

Sponsors & Collaborators

• Centre d'Investigation Clinique et Technologique 805: lead

Study Sites (1)

Raymond Poincaré

Garches, 92380, France

RECRUITING

Related Publications (5)

• You K, Yang HT, Kym D, Yoon J, HaejunYim, Cho YS, Hur J, Chun W, Kim JH. Inhalation injury in burn patients: establishing the link between diagnosis and prognosis. Burns. 2014 Dec;40(8):1470-5. doi: 10.1016/j.burns.2014.09.015. Epub 2014 Oct 16.

  PMID: 25406889 BACKGROUND

• Kim Y, Kym D, Hur J, Yoon J, Yim H, Cho YS, Chun W. Does inhalation injury predict mortality in burns patients or require redefinition? PLoS One. 2017 Sep 27;12(9):e0185195. doi: 10.1371/journal.pone.0185195. eCollection 2017.

  PMID: 28953914 BACKGROUND

• Darling GE, Keresteci MA, Ibanez D, Pugash RA, Peters WJ, Neligan PC. Pulmonary complications in inhalation injuries with associated cutaneous burn. J Trauma. 1996 Jan;40(1):83-9. doi: 10.1097/00005373-199601000-00016.

  PMID: 8577005 BACKGROUND

• Liao WC, Cheng WC, Wu BR, Chen WC, Chen CY, Chen CH, Tu CY, Hsia TC. Outcome and prognostic factors of patients treated in the intensive care unit for carbon monoxide poisoning. J Formos Med Assoc. 2019 Apr;118(4):821-827. doi: 10.1016/j.jfma.2018.09.005. Epub 2018 Oct 5.

  PMID: 30293927 BACKGROUND

• Raphael JC, Annane D, Chevret S. Hyperbaric oxygen for acute carbon monoxide poisoning. N Engl J Med. 2003 Feb 6;348(6):557-60; author reply 557-60. No abstract available.

  PMID: 12572578 BACKGROUND

MeSH Terms

Conditions

Smoke Inhalation Injury

Condition Hierarchy (Ancestors)

Burns, Inhalation; Burns; Wounds and Injuries

Study Officials

• Rania BOUNAB, dr

  Raymond Poincaré Hospital

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Rania BOUNAB, Dr

CONTACT

+33 (1) 74 10 7778; rania.bounab@aphp.fr

Fatima IZEDAREN, CRA

CONTACT

+33 (1) 47 10 44 49; fatima.izedaren@aphp.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 21, 2018
• First Posted: February 7, 2019
• Study Start: October 16, 2018
• Primary Completion: December 31, 2019
• Study Completion: May 31, 2020
• Last Updated: February 7, 2019

Record last verified: 2018-11

Locations

FR (1)