NCT03824821

Brief Summary

This study is a cross-sectional observational study design that aimed to include 2000 IBS patients. We used several validated questionnaires, to assess IBS characteristics (such as subtype, severity), psychological features (QoL, anxiety and depression) and assess nutritional triggers. Subjects filled in the questionnaire online, and was spread across the Netherlands.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,076

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2018

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 22, 2018

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 31, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2018

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

January 29, 2019

Completed
2 days until next milestone

First Posted

Study publicly available on registry

January 31, 2019

Completed
Last Updated

January 31, 2019

Status Verified

January 1, 2019

Enrollment Period

4 months

First QC Date

January 29, 2019

Last Update Submit

January 30, 2019

Conditions

Keywords

NutritionIrritable Bowel SyndromeQuality of Life

Outcome Measures

Primary Outcomes (4)

  • IBS subtype

    Assessed using the Validated Bristol stool chart

    1 day (once )

  • IBS severity

    Assessed by the validated Symptom severity scale (IBS-SSS), rangeing from 0 - 500; 0 very low and 500 very severe case

    1 day (once )

  • Nutrition questionnaire

    We composed a questionnaire containing 44 identified nutritional triggers from literature, and asked subjects if they had (0, no complaints), 1 little complaints, 2 severe complaints, after eating that product.

    1 day (once )

  • Birmingham symptom questionnaire

    Validated questionnaire that assesses symptoms for three domains: pain, diarrhoea and constipation

    1 day (once )

Secondary Outcomes (4)

  • Irritable bowel syndrome Quality of Life questionnaire

    1 day (once )

  • Hospital Anxiety and Depression Score (HADS)

    1 day (once )

  • treatment options currently used

    1 day (once )

  • Rome IV criteria

    1 day (once )

Study Arms (1)

IBS

Other: No intervention

Interventions

No intervention

IBS

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

There were no strict inclusion and exclusion criteria, since many IBS patients do not have an official diagnosis of IBS. therefore, the ROME IV diagnostic criteria were included in the questionnaire, to assess whether subjects fit within the IBS profile.

You may qualify if:

  • IBS-like symptoms

You may not qualify if:

  • younger than 18 years

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Wageningen University & Research

Wageningen, 6700 VB, Netherlands

Location

MeSH Terms

Conditions

Irritable Bowel Syndrome

Condition Hierarchy (Ancestors)

Colonic Diseases, FunctionalColonic DiseasesIntestinal DiseasesGastrointestinal DiseasesDigestive System Diseases

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 29, 2019

First Posted

January 31, 2019

Study Start

January 22, 2018

Primary Completion

May 31, 2018

Study Completion

May 31, 2018

Last Updated

January 31, 2019

Record last verified: 2019-01

Locations