NCT03818750

Brief Summary

Impact of marketing of alcohol products on young people

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
78

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jun 2018

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 13, 2018

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

September 5, 2018

Completed
5 months until next milestone

First Posted

Study publicly available on registry

January 28, 2019

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 7, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 7, 2019

Completed
Last Updated

March 11, 2019

Status Verified

March 1, 2019

Enrollment Period

9 months

First QC Date

September 5, 2018

Last Update Submit

March 8, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Changes in brain activation in areas involved in the control of reward and motivation when looking at neutral versus contextual ads

    Significant change in cerebral activity (expressed as a significant variation in hemodynamic response BOLD) in the condition of alcohol ads with versus without context (party, sport, people) in areas involved in the control of reward and motivation (striatum dorsal, insula)

    Month 1

Study Arms (1)

Experimental arm

EXPERIMENTAL

Patients (60) will be selected from the Alcohol Use Disorders Identification Test (AUDIT-C) : * "light drinkers" (score between 1 to 3) * "heavy drinkers" (score between 4 to 7) Two clinical visits will be realized in less than 4 weeks

Device: MRIBehavioral: Alcohol Use Disorders Identification Test

Interventions

MRIDEVICE

Subjects review alcohol ads in different contexts (neutral context vs positive context such as parties and sport) and answer with buttons lever while being in the MRI to express their desire to consume alcohol or not. Subjects will be exposed to 288 ads set up.

Experimental arm

Questionnaire

Experimental arm

Eligibility Criteria

Age18 Years - 25 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • volunteer males
  • aged 18-25
  • right-handed
  • persons that consume alcohol : " light drinkers " or "heavy drinkers" (defined with the AUDIT scale, scores between 1 to 7)
  • written consent and agreement consent will be given
  • Affiliated to the French social insurance

You may not qualify if:

  • color-blind persons
  • misuse of psychoactive products (except tobacco) (cannabis : no regular consumers -more than 10 times per month ; no users of other illicit drugs - even for occasional consumption)
  • non fluent french speaking persons (people who couldn't understand instructions or asked questions)
  • persons subject to major legal protection (safeguarding justice, guardianship, trusteeship), persons deprived of liberty
  • Related to the MRI:
  • Cardiac pacemaker or implanted defibrillator
  • Cochlear implant
  • Peripheral or neuronal stimulator
  • Intra-ocular or brain metallic foreign bodies
  • Any other contraindications to MRI

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU de Rennes

Rennes, 35033, France

Location

MeSH Terms

Conditions

Alcoholism

Interventions

Ethanol

Condition Hierarchy (Ancestors)

Alcohol-Related DisordersSubstance-Related DisordersChemically-Induced DisordersMental Disorders

Intervention Hierarchy (Ancestors)

AlcoholsOrganic Chemicals

Study Officials

  • Romain Moirand, MD, PhD

    CHU of Rennes

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 5, 2018

First Posted

January 28, 2019

Study Start

June 13, 2018

Primary Completion

March 7, 2019

Study Completion

March 7, 2019

Last Updated

March 11, 2019

Record last verified: 2019-03

Data Sharing

IPD Sharing
Will not share

Locations