NCT03815760

Brief Summary

The purpose of this study is to evaluate the ability of blood flow restriction therapy to improve strength of shoulder muscles during the sidelying external rotation (ER) exercise versus a control group who only performs the sidelying ER exercise.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2019

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 17, 2019

Completed
1 day until next milestone

Study Start

First participant enrolled

January 18, 2019

Completed
6 days until next milestone

First Posted

Study publicly available on registry

January 24, 2019

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 30, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 30, 2019

Completed
Last Updated

January 24, 2019

Status Verified

January 1, 2019

Enrollment Period

4 months

First QC Date

January 17, 2019

Last Update Submit

January 22, 2019

Conditions

Keywords

infraspinatus, external rotators, blood flow restriction

Outcome Measures

Primary Outcomes (2)

  • Muscular Strength as Measured by Dynamometry

    Use a hand held dynamometer (MicroFet 2) to measure strength of the middle and posterior deltoid, the supraspinatus, and the infraspinatus

    Change from Baseline to 8-weeks

  • Tendon Size as Measured by Diagnostic Ultrasound

    Ultrasound images are capture at pre- and post-test sessions

    Change from Baseline to 8-weeks

Study Arms (2)

Exercise with Blood Flow Restriction

EXPERIMENTAL

Subjects will perform the sidelying external rotation exercise 2x a week for 8 weeks. The BFR cuff will be applied to the upper arm. Arterial occlusion will be set to 50%. Subjects will perform 4 sets (30, 15, 15, 15 reps) with a 30 sec rest period between reps. The occlusion will be maintained for the 8 min treatment period.

Device: Blood Flow Restriction

Exercise without Blood Flow Restriction

ACTIVE COMPARATOR

Subjects will perform the sidelying external rotation exercise 2x a week for 8 weeks. This group will not have BFR applied. Subjects will perform 4 sets (30, 15, 15, 15 reps) with a 30 sec rest period between reps.

Device: Blood Flow Restriction

Interventions

Subjects will perform sidelying external rotation exercise

Also known as: Exercise
Exercise with Blood Flow RestrictionExercise without Blood Flow Restriction

Eligibility Criteria

Age18 Years - 45 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • \. Healthy adult (age 18 and older) with no current shoulder pathology

You may not qualify if:

  • Current neck, shoulder (or general upper extremity), and/or thoracic spine pathology
  • Shoulder surgery (or general upper extremity surgery) during the prior 6-month time period
  • Cervical/thoracic spine surgery during the prior 1 year
  • Subject having one or more contraindications for BFR training.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

George Fox University School of Physical Therapy

Newberg, Oregon, 97132, United States

RECRUITING

MeSH Terms

Conditions

Muscle Weakness

Interventions

Blood Flow Restriction TherapyExercise Therapy

Condition Hierarchy (Ancestors)

Muscular DiseasesMusculoskeletal DiseasesNeuromuscular ManifestationsNeurologic ManifestationsNervous System DiseasesPathologic ProcessesPathological Conditions, Signs and SymptomsSigns and Symptoms

Intervention Hierarchy (Ancestors)

RehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsPhysical Therapy Modalities

Study Officials

  • Jason Brumitt, PhD

    George Fox University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Jason Brumitt, PhD

CONTACT

Tyler Cuddeford, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Outcomes assessors are blinded to group allocation.
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor of Physical Therapy

Study Record Dates

First Submitted

January 17, 2019

First Posted

January 24, 2019

Study Start

January 18, 2019

Primary Completion

May 30, 2019

Study Completion

May 30, 2019

Last Updated

January 24, 2019

Record last verified: 2019-01

Data Sharing

IPD Sharing
Will not share

Locations