NCT03791138

Brief Summary

This study evaluates the impact of an online patient decision aid on the process of decision making regarding breast reconstruction and the decision quality in women with breast cancer undergoing mastectomy and considering immediate breast reconstruction. Half of participants will receive care as usual and access to the online decision aid, while the other half will receive care as usual including a standard information leaflet.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
250

participants targeted

Target at P75+ for not_applicable breast-cancer

Timeline
Completed

Started Aug 2017

Typical duration for not_applicable breast-cancer

Geographic Reach
1 country

8 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 16, 2017

Completed
1.3 years until next milestone

First Submitted

Initial submission to the registry

December 17, 2018

Completed
16 days until next milestone

First Posted

Study publicly available on registry

January 2, 2019

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 28, 2019

Completed
1.4 years until next milestone

Study Completion

Last participant's last visit for all outcomes

October 8, 2020

Completed
Last Updated

June 6, 2022

Status Verified

June 1, 2022

Enrollment Period

1.8 years

First QC Date

December 17, 2018

Last Update Submit

June 3, 2022

Conditions

Keywords

breast reconstructionpatient decision aiddecisional conflictrandomized controlled trial

Outcome Measures

Primary Outcomes (1)

  • decisional conflict

    decisional conflict scale (DCS); the DCS consists of a total score and five subscales (uncertainty, feeling informed, feeling clear about values, feeling supported and effective decision-making). It consists of 16 items which are rated on a 5-point Likert-type scale (strongly agree- strongly disagree). Scores range from 0 - 100, with higher scores indicating more decisional conflict.

    1 week after consultation with a plastic surgeon (T1)

Secondary Outcomes (13)

  • decisional conflict

    3 months after surgery (T2); 12 months after surgery (T3)

  • decision regret

    3 months after surgery (T2); 12 months after surgery (T3)

  • knowledge about breast reconstruction

    1 week after consultation with plastic surgeon (T1); 3 months after surgery (T2); 12 months after surgery (T3)

  • preparedness for decision making

    1 week after consultation with a plastic surgeon (T1)

  • satisfaction with information

    1 week after consultation with plastic surgeon (T1); 3 months after surgery (T2); 12 months after surgery (T3)

  • +8 more secondary outcomes

Study Arms (2)

intervention group

EXPERIMENTAL

Care as usual and an online patient decision aid

Other: online patient decision aid

control group

NO INTERVENTION

Care as usual with a standard information leaflet

Interventions

An online, interactive tool that can be used to prepare for consultation with a plastic surgeon which contains evidence-based information about breast reconstruction options, the pros and cons of the options, value clarification exercises and patient narratives. It results in a summary sheet with patients' personal values and questions that can be discussed during consultation with a plastic surgeon.

Also known as: Breast Reconstruction Decision Aid
intervention group

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • female (≥18 years);
  • diagnosed with breast cancer or carcinoma in situ;
  • will be treated with mastectomy and is eligible for immediate breast reconstruction;
  • is referred to a plastic surgeon (consultation takes place ≥3 working days after study invitation);
  • has internet access and sufficient computer skills;
  • is able to read and speak the Dutch language.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (8)

Meander Medical Center

Amersfoort, Netherlands

Location

Medical Center Slotervaart

Amsterdam, Netherlands

Location

Netherlands Cancer Institute

Amsterdam, Netherlands

Location

Reinier de Graaf Gasthuis

Delft, Netherlands

Location

Medical Center Leeuwarden

Leeuwarden, Netherlands

Location

Erasmus Medical Center

Rotterdam, Netherlands

Location

Franciscus Gasthuis & Vlietland

Rotterdam, Netherlands

Location

University Medical Center Utrecht

Utrecht, Netherlands

Location

Related Publications (2)

  • Ter Stege JA, Woerdeman LAE, Kieffer JM, Sherman KA, Agelink van Rentergem JA, van Duijnhoven FH, van Huizum MA, Gerritsma MA, Kuenen M, Corten EML, Kimmings NAN, Ruhe QPQ, Krabbe-Timmerman IS, Van't Riet M, Hahn DEE, Witkamp AJ, Oldenburg HSA, Bleiker EMA. Efficacy of a Decision Aid in Breast Cancer Patients Considering Immediate Reconstruction: Results of a Randomized Controlled Trial. Plast Reconstr Surg. 2024 Oct 1;154(4):706-722. doi: 10.1097/PRS.0000000000011100. Epub 2023 Oct 9.

  • Ter Stege JA, Woerdeman LAE, Hahn DEE, van Huizum MA, van Duijnhoven FH, Kieffer JM, Retel VP, Sherman KA, Witkamp AJ, Oldenburg HSA, Bleiker EMA. The impact of an online patient decision aid for women with breast cancer considering immediate breast reconstruction: study protocol of a multicenter randomized controlled trial. BMC Med Inform Decis Mak. 2019 Aug 19;19(1):165. doi: 10.1186/s12911-019-0873-1.

MeSH Terms

Conditions

Breast Neoplasms

Condition Hierarchy (Ancestors)

Neoplasms by SiteNeoplasmsBreast DiseasesSkin DiseasesSkin and Connective Tissue Diseases

Study Officials

  • Eveline MA Bleiker, Professor

    The Netherlands Cancer Institute

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 17, 2018

First Posted

January 2, 2019

Study Start

August 16, 2017

Primary Completion

May 28, 2019

Study Completion

October 8, 2020

Last Updated

June 6, 2022

Record last verified: 2022-06

Data Sharing

IPD Sharing
Will not share

Locations