Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 60/100

Failure Rate

11.3%

36 terminated/withdrawn out of 320 trials

Success Rate

75.0%

-11.5% vs industry average

Late-Stage Pipeline

11%

35 trials in Phase 3/4

Results Transparency

5%

5 of 108 completed trials have results

Key Signals

75 recruiting5 with results31 terminated5 withdrawn

Enrollment Performance

Analytics

N/A
87(34.4%)
Phase 2
80(31.6%)
Phase 1
47(18.6%)
Phase 3
32(12.6%)
Early Phase 1
4(1.6%)
Phase 4
3(1.2%)
253Total
N/A(87)
Phase 2(80)
Phase 1(47)
Phase 3(32)
+2 more

Activity Timeline

Global Presence

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Clinical Trials (320)

Showing 20 of 320 trials
NCT07402343Phase 2Not Yet Recruiting

Tarlatamab for SCLC Brain Metastases

Role: collaborator

NCT04071704Completed

Assessing Health-related Quality of Life in Sarcoma Patients

Role: lead

NCT03540420Phase 2Active Not Recruiting

Atezolizumab After Concurrent Chemo-radiotherapy Versus Chemo-radiotherapy Alone in Limited Disease Small-cell Lung Cancer

Role: collaborator

NCT07522762Recruiting

Long-term Survivorship Challenges of Advanced/Metastatic GIST Patients Responding to Tyrosine Kinase Inhibitor Treatment: an Observational Study

Role: lead

NCT03772028Phase 3Active Not Recruiting

Primary Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

Role: lead

NCT07485452Phase 2Not Yet Recruiting

Boosting Osimertinib Blood Brain Barrier Penetration

Role: collaborator

NCT07486687Phase 3Not Yet Recruiting

Pembrolizumab Adjuvant in Patients With Early-stage Triple Negative Breast Cancer With Residual Disease After Neoadjuvant Pembrolizumab Plus Chemotherapy

Role: lead

NCT05529927Phase 2Not Yet Recruiting

Efficacy and Safety of Sustained-release Dexamphetamine in Patients With Moderate to Severe Cocaine Use Disorder

Role: collaborator

NCT05401786Phase 2Active Not Recruiting

Anti-PD-1 Re-challenge After Immune Priming by Ipilimumab and Immune Boosting by Radiotherapy in Advanced NSCLC

Role: lead

NCT07460180Phase 1Recruiting

The PROOV Study: Exploiting the Synergistic Effect of PARP Inhibition With Cisplatin and Hyperthermia During Interval Cytoreductive Surgery and HIPEC in Ovarian Cancer

Role: lead

NCT06279130Phase 2Recruiting

Pan-tumor Neoadjuvant Basket Study of Immune Check-point Inhibition and Novel Immuno-oncology Combinations

Role: lead

NCT03026140Phase 2Recruiting

Neoadjuvant Immune Checkpoint Inhibition and Novel IO Combinations in Early-stage Colon Cancer

Role: lead

NCT04075305Recruiting

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

Role: collaborator

NCT03564197Not ApplicableCompleted

18F-PD-L1 PET/CT in Nivolumab Treated Patients With NSCLC

Role: lead

NCT07436858Phase 1Not Yet Recruiting

Whole Body HER2 Quantification With 89Zr-Trastuzumab PET/CT to Asses Zr-trastuzumab Accumulation in HER2-mutated and HER2-overexpressing Metastatic Non-small Cell Lung Cancer

Role: lead

NCT06888817Phase 3Recruiting

Bevacizumab Versus Corticosteroids as First-line Treatment in Patients With Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain Metastases

Role: lead

NCT04678011Recruiting

A Personalized Surveillance and Intervention Protocol for Patients With Familial Adenomatous Polyposis That Have Undergone (Procto)Colectomy

Role: collaborator

NCT04677998Recruiting

A Personalized Surveillance and Intervention Protocol for Duodenal and Gastric Polyposis in Patients With Familial Adenomatous Polyposis

Role: collaborator

NCT07071727Not ApplicableRecruiting

Short Course of Radiotherapy Prior to Surgery of Soft Tissue Sarcomas

Role: lead

NCT07391982Not ApplicableRecruiting

Dose De-escalation in Prostate Radiotherapy Using an MR-Linac in Two Fractions

Role: lead