NCT03779828

Brief Summary

Chronic inflammatory demyelinating polyneuropathy (CIDP) is a chronic demyelinating polyneuropathy of autoimmune origin with a progressive or relapsing course. Diagnosis is based on clinical presentation and electrophysiological findings in accordance with the EFNS/PNS consensus guidelines. IVIg is the first line treatment witch has been shown to be effective in several placebo-controlled trials. Once IVIg therapy produces a response and is well tolerated, some patients are able to continue their treatment in the home setting. The HOME LINK system offers an integrated, global solution based on telemonitoring technology providing continuous, remote monitoring of Privigen® infusions administered at home.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
11

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Nov 2017

Geographic Reach
1 country

10 active sites

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 27, 2017

Completed
1 year until next milestone

First Submitted

Initial submission to the registry

December 14, 2018

Completed
5 days until next milestone

First Posted

Study publicly available on registry

December 19, 2018

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 3, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 3, 2019

Completed
Last Updated

January 15, 2021

Status Verified

January 1, 2021

Enrollment Period

1.5 years

First QC Date

December 14, 2018

Last Update Submit

January 13, 2021

Conditions

Keywords

CIDPTelemonitoringTelemedicine

Outcome Measures

Primary Outcomes (1)

  • Evaluate HOME LINK telemonitoring system for patients receiving home-based IVIg therapy

    The conventional method of home monitoring requires using a visiting nurse. HOME LINK is a telemonitoring system that is an alternative to this conventional method offering remote at-home monitoring. HOME LINK monitors the patient's health parameters from home. In this way it enables an adjustment of the infusion conditions or intervention of a qualified healthcare professional in the event of an incident. Home Link will be evaluated for failure rate of connection to the telemonitoring platform, failure rate of transmission of self-measurements to the telemonitoring platform, failure rate of transmission of documents relating to home-based treatment, and failure rate of contacting one of the healthcare professionals involved in patient care during the at-home infusions.

    52 weeks

Interventions

HOME LINKDEVICE

Telemonitoring system which include web platform and connected devices.

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients receiving home-based IVIg therapy with Privigen

You may qualify if:

  • Patient with a diagnosis of CIDP as per EFNS/PNS criteria.
  • Patient already receiving home-based treatment with Privigen®

You may not qualify if:

  • Not applicable

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (10)

Hôpital Pellegrin, Bordeaux University Hospital (CHU)

Bordeaux, France

Location

Hôpital Henri Mondor - APHP

Créteil, France

Location

Hôpital Roger Salengro - CHRU

Lille, France

Location

Hôpital Pierre Wertheimer - HCL

Lyon, France

Location

Hôpital La Timone - APHM

Marseille, France

Location

Hôpital Gui de Chauliac - Montpellier University Hospital (CHU)

Montpellier, France

Location

Hôpital Pasteur 2 - Nice University Hospital (CHU)

Nice, France

Location

Hôpital La Pitié-Salpêtrière - APHP

Paris, France

Location

Hôpital Lariboisière - APHP

Paris, France

Location

Hôpital Nord - Saint Etienne University Hospital (CHU)

Saint-Etienne, France

Location

MeSH Terms

Conditions

Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

Condition Hierarchy (Ancestors)

PolyradiculoneuropathyAutoimmune Diseases of the Nervous SystemNervous System DiseasesDemyelinating DiseasesPolyneuropathiesPeripheral Nervous System DiseasesNeuromuscular DiseasesAutoimmune DiseasesImmune System DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 14, 2018

First Posted

December 19, 2018

Study Start

November 27, 2017

Primary Completion

June 3, 2019

Study Completion

June 3, 2019

Last Updated

January 15, 2021

Record last verified: 2021-01

Data Sharing

IPD Sharing
Will not share

Locations