NCT03776097

Brief Summary

The objective of this non-interventional long-term follow-up observation is to evaluate the long-term sustainability of two surgical treatments of peri-implantitis with and without Geistlich Bio-Oss® and Geistlich Bio-Gide® from a previous study

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
59

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Dec 2015

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2015

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

August 8, 2016

Completed
2.4 years until next milestone

First Posted

Study publicly available on registry

December 14, 2018

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 21, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 21, 2019

Completed
Last Updated

August 28, 2019

Status Verified

August 1, 2019

Enrollment Period

3.3 years

First QC Date

August 8, 2016

Last Update Submit

August 23, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Defect fill

    The primary outcome measure will be the change of "bone levels"(defect fill) over 2 years starting 1 year after surgical Intervention as assessed from intra-oral radiographs. In particular, the distances between the most apical implant to bone contact level and a characteristic reference point being the same for all sets of radiographs will be measured. The distance equal to three implant threads (known for the implant system) will be measured with a specific Software. The deeper bone level at baseline will be considered

    2 years after the start of the study

Study Arms (2)

Defect Fill.

Observational study of the patients that were treated with biomaterials at the surgery in the previous study

Other: observational study

No defect Fill.observational

Observational study of the patients that were not treated with biomaterials at the surgery of te previous study

Other: observational study

Interventions

Observational study

Defect Fill.No defect Fill.observational

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

patients from a previous study

You may qualify if:

  • Implant survival at the treated site from the previous study
  • Written informed consent

You may not qualify if:

  • Implant failure at the treated site
  • Severe trauma to implant site causing removal of the implant since the last visit of previous study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kristianstad University

Kristianstad, Sweden

Location

MeSH Terms

Conditions

Peri-Implantitis

Interventions

Observation

Condition Hierarchy (Ancestors)

Periodontal DiseasesMouth DiseasesStomatognathic Diseases

Intervention Hierarchy (Ancestors)

MethodsInvestigative Techniques

Study Officials

  • Silvia Rasi, PhD

    Geistlich Pharma

    STUDY DIRECTOR
  • Stefan Renvert

    Kristianstadt University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 8, 2016

First Posted

December 14, 2018

Study Start

December 1, 2015

Primary Completion

March 21, 2019

Study Completion

March 21, 2019

Last Updated

August 28, 2019

Record last verified: 2019-08

Locations