Ten Years Follow up of Peri-implant Surgery

NCT04254406 | Completed

• 1 other identifier: PDSSweden
• Study Type: observational
• Target: 41
• Locations: 1 country
• Sites: 1

Brief Summary

To report 10-years follow up of patients following the surgical treatment of peri-implantitis and to identify possible risk indicators for the progression of disease during supportive peri-implant therapy.

Conditions

Peri-Implantitis

Keywords

Peri-Implantitis surgery; Treatment outcome; Risk factors

Outcome Measures

Primary Outcomes (4)

• Number patients with persisting peri-implantitis following peri-implant surgery

  The total number of patients with persisting peri-implantitis will be calculated. Any subject presenting at least one implants with a pathological pocket will be regarded as positive for the disease . The presence or absence of peri-implantitis will be assessed by using a periodontal probe around the mucosa of the implants. The definition of a pathological pocket around an implant is a pocket of 5 millimeters or more deep with concomitants bleeding after the use of the probe.

  10 years

• Percentage of subjects with persisting peri-implantitis

  The percentage of patients with persisting peri-implantitis following peri-implantitis surgery will be calculated among all the patients that were treated. For definition of peri-implantitis see description at outcome 1.

  10 years

• Number of implant with persisting peri-implantitis

  The number of implants with persisting clinical signs of peri-implantitis will be calculated. Any implant presenting a pathological pockets around its surface will be regarded as positive for the disease. For definition of peri-implantitis see description at outcome 1

  10 years

• Percentage of implants wih persisting peri-implantitis

  The percentage of implants with persisting peri-implantitis after surgery will be calculated among all the implants that were surgically treated. For definition of peri-implantitis see description at outcome 1

  10 years

Secondary Outcomes (1)

• Assessement of risk factors related to the persistence of peri-implantitis

  10 years

Interventions

Descriptive study OTHER

Evaluation of routine treatment

Eligibility Criteria

• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Consecutive patients who had received routine surgical treatment of peri-implantitis between 2007 and 2009 and thereafter enrolled in supportive peri-implant treatment (SPT)

You may qualify if:

• \- All patients treated with peri-implantitis surgery between 2007 and 2009 using an anti-infective protocol.

You may not qualify if:

• Patients treated with peri-implantitis surgery between 2007 and 2009 using a regenerative protocol at one single implants with peri-implantitis.

Sponsors & Collaborators

• Public Dental Service, Specialist Clinics, Sweden: lead
• Osaka University Japan: collaborator

Study Sites (1)

Giovanni Serino

Borås, 50182, Sweden

Location

Related Publications (7)

• Heitz-Mayfield LJA, Salvi GE, Mombelli A, Loup PJ, Heitz F, Kruger E, Lang NP. Supportive peri-implant therapy following anti-infective surgical peri-implantitis treatment: 5-year survival and success. Clin Oral Implants Res. 2018 Jan;29(1):1-6. doi: 10.1111/clr.12910. Epub 2016 Jun 23.

  PMID: 27335316 RESULT

• Serino G, Turri A, Lang NP. Maintenance therapy in patients following the surgical treatment of peri-implantitis: a 5-year follow-up study. Clin Oral Implants Res. 2015 Aug;26(8):950-956. doi: 10.1111/clr.12418. Epub 2014 May 26.

  PMID: 24861154 RESULT

• Serino G, Turri A. Outcome of surgical treatment of peri-implantitis: results from a 2-year prospective clinical study in humans. Clin Oral Implants Res. 2011 Nov;22(11):1214-20. doi: 10.1111/j.1600-0501.2010.02098.x. Epub 2011 Feb 11.

  PMID: 21309860 RESULT

• Roccuzzo M, Layton DM, Roccuzzo A, Heitz-Mayfield LJ. Clinical outcomes of peri-implantitis treatment and supportive care: A systematic review. Clin Oral Implants Res. 2018 Oct;29 Suppl 16:331-350. doi: 10.1111/clr.13287.

  PMID: 30328195 RESULT

• Berglundh T, Armitage G, Araujo MG, Avila-Ortiz G, Blanco J, Camargo PM, Chen S, Cochran D, Derks J, Figuero E, Hammerle CHF, Heitz-Mayfield LJA, Huynh-Ba G, Iacono V, Koo KT, Lambert F, McCauley L, Quirynen M, Renvert S, Salvi GE, Schwarz F, Tarnow D, Tomasi C, Wang HL, Zitzmann N. Peri-implant diseases and conditions: Consensus report of workgroup 4 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J Clin Periodontol. 2018 Jun;45 Suppl 20:S286-S291. doi: 10.1111/jcpe.12957.

  PMID: 29926491 RESULT

• Lagervall M, Jansson LE. Treatment outcome in patients with peri-implantitis in a periodontal clinic: a retrospective study. J Periodontol. 2013 Oct;84(10):1365-73. doi: 10.1902/jop.2012.120555. Epub 2012 Dec 13.

  PMID: 23237584 RESULT

• Pjetursson BE, Helbling C, Weber HP, Matuliene G, Salvi GE, Bragger U, Schmidlin K, Zwahlen M, Lang NP. Peri-implantitis susceptibility as it relates to periodontal therapy and supportive care. Clin Oral Implants Res. 2012 Jul;23(7):888-94. doi: 10.1111/j.1600-0501.2012.02474.x. Epub 2012 Apr 24.

  PMID: 22530771 RESULT

MeSH Terms

Conditions

Peri-Implantitis

Condition Hierarchy (Ancestors)

Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases

Study Officials

• Giovanni Serino, DDS PhD

  Folktanvarden Specilist Clinic Periodntology

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Head of Department of Periodontology

Study Record Dates

• First Submitted: January 24, 2020
• First Posted: February 5, 2020
• Study Start: January 1, 2019
• Primary Completion: October 1, 2019
• Study Completion: October 1, 2019
• Last Updated: February 5, 2020

Record last verified: 2020-02

Data Sharing

• IPD Sharing: Will not share

Locations

SE (1)