Evaluation of Micro-osteoperforation on Rate of Maxillary En-masse Retraction

NCT03764189 | Unknown DMC

• 1 other identifier: CEBD-CU-2018-11-41
• Study Type: interventional
• Target: 13
• Locations: 1 country
• Sites: 1

Brief Summary

accelerated anterior teeth retraction with the help of microosteoperforation procedure and miniscrews.

Conditions

Class II Division 1 Malocclusion

Keywords

Accelerated tooth movement AND anterior segment retraction AND miniscrews AND microosteoperforation

Outcome Measures

Primary Outcomes (1)

• Rate of En-masse retraction

  retracting six anterior teeth

  three to six months

Secondary Outcomes (3)

• Root resorption affecting the six anterior teeth.

  three to six months

• Tipping affecting the anterior teeth.

  three to six months

• Extrusion of anterior teeth

  three to six months

Study Arms (2)

en masse retraction only

NO INTERVENTION

anterior segment retraction on miniscrews without microosteoperforation

en masse retraction with alveocentesis

ACTIVE COMPARATOR

anterior segment retraction on miniscrews with microosteoperforation

Procedure: microosteoperforation

Interventions

microosteoperforation PROCEDURE

small holes made using large round bur

Also known as: accelerated tooth movement, alveocentesis

en masse retraction with alveocentesis

Eligibility Criteria

• Age: 16 Years - 30 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Females with an age ranging between 16-30 years.
• Malocclusion that requires bilateral extraction of the maxillary first premolars and anterior segment retraction; Angle class I mal-occlusion with bi-alveolar dental protrusions or class II division 1.
• Healthy dental and periodontal condition with a good oral hygiene
• Absence of degenerative conditions.
• Full set of permanent dentition.

You may not qualify if:

• Medically compromised patients.
• Previous orthodontic treatment
• Patients suffering from any congenital, hereditary or systemic diseases or asymmetries that might have an influence on tooth movement
• Chronic use of any medications affecting orthodontic tooth movement (eg: NSAIDs).
• Active periodontal affection or severe gingival inflammation.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Cairo University

Cairo, Giza Governorate, 12566, Egypt

Location

Related Publications (10)

• McGorray SP, Dolce C, Kramer S, Stewart D, Wheeler TT. A randomized, placebo-controlled clinical trial on the effects of recombinant human relaxin on tooth movement and short-term stability. Am J Orthod Dentofacial Orthop. 2012 Feb;141(2):196-203. doi: 10.1016/j.ajodo.2011.07.024.

  PMID: 22284287 BACKGROUND

• Nicozisis, J., Accelerated Orthodontics With Alveocentesis. Princeton Orthodontics. Clin Orthod, 2012. 19: p. 1-4

  BACKGROUND

• Collins MK, Sinclair PM. The local use of vitamin D to increase the rate of orthodontic tooth movement. Am J Orthod Dentofacial Orthop. 1988 Oct;94(4):278-84. doi: 10.1016/0889-5406(88)90052-2.

  PMID: 3177281 BACKGROUND

• Blanco, J., et al., Efecto de la administración sistémica del 1, 25 Dihidrxicolecalciferol sobre la velocidad del movimiento ortodóncico en humanos. Estudio Clínico. Revista Odontos, 2001. 8: p. 13-21

  BACKGROUND

• Cruz DR, Kohara EK, Ribeiro MS, Wetter NU. Effects of low-intensity laser therapy on the orthodontic movement velocity of human teeth: a preliminary study. Lasers Surg Med. 2004;35(2):117-20. doi: 10.1002/lsm.20076.

  PMID: 15334614 BACKGROUND

• Alfawal AMH, Hajeer MY, Ajaj MA, Hamadah O, Brad B. Evaluation of piezocision and laser-assisted flapless corticotomy in the acceleration of canine retraction: a randomized controlled trial. Head Face Med. 2018 Feb 17;14(1):4. doi: 10.1186/s13005-018-0161-9.

  PMID: 29454369 BACKGROUND

• Alikhani, M., et al. Micro-osteoperforations: minimally invasive accelerated tooth movement. in Seminars in Orthodontics. 2015. Elsevier

  BACKGROUND

• Alikhani M, Raptis M, Zoldan B, Sangsuwon C, Lee YB, Alyami B, Corpodian C, Barrera LM, Alansari S, Khoo E, Teixeira C. Effect of micro-osteoperforations on the rate of tooth movement. Am J Orthod Dentofacial Orthop. 2013 Nov;144(5):639-48. doi: 10.1016/j.ajodo.2013.06.017.

  PMID: 24182579 BACKGROUND

• Ribeiro GL, Jacob HB. Understanding the basis of space closure in Orthodontics for a more efficient orthodontic treatment. Dental Press J Orthod. 2016 Mar-Apr;21(2):115-25. doi: 10.1590/2177-6709.21.2.115-125.sar.

  PMID: 27275623 BACKGROUND

• Kau CH, Kantarci A, Shaughnessy T, Vachiramon A, Santiwong P, de la Fuente A, Skrenes D, Ma D, Brawn P. Photobiomodulation accelerates orthodontic alignment in the early phase of treatment. Prog Orthod. 2013 Sep 19;14:30. doi: 10.1186/2196-1042-14-30.

  PMID: 24326198 RESULT

MeSH Terms

Conditions

Malocclusion, Angle Class II

Condition Hierarchy (Ancestors)

Malocclusion; Tooth Diseases; Stomatognathic Diseases

Study Officials

• Mohamed A Kaddah, Phd

  Cairo u

  STUDY DIRECTOR

Central Study Contacts

Nashwa abdel m mohamed, master

CONTACT

01020271313; dr.nashwa_87@live.com

Eman m el sayed, Phd

CONTACT

01005289453

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Masking Details: not possible as the subject will sign an informed consent and areas of microosteoperforation will be apparent
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principal investigator

Study Record Dates

• First Submitted: December 1, 2018
• First Posted: December 5, 2018
• Study Start: January 1, 2019
• Primary Completion: November 1, 2020
• Study Completion: November 1, 2020
• Last Updated: December 7, 2018

Record last verified: 2018-12

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)