Perfusion and Dual Energy Computer Tomography in Hepatocellular Carcinoma
PERCAHEC
Prediction Value of Perfusion and Dual Energy Computer Tomography for Microvascular Invasion in Hepatocellular Carcinoma
1 other identifier
interventional
50
1 country
1
Brief Summary
The aim of this study is to evaluate the hepatic perfusion computer tomography and dual energy computer tomography in the assessment of tumor characterization of Hepatocellular carcinoma in patients with resectable Hepatocellular carcinoma by comparing the quantitative parameters computer tomography obtained with the pathological data of the surgical specimens.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable hepatocellular-carcinoma
Started Jan 2019
Shorter than P25 for not_applicable hepatocellular-carcinoma
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
November 14, 2018
CompletedFirst Posted
Study publicly available on registry
November 27, 2018
CompletedStudy Start
First participant enrolled
January 30, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 30, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
December 30, 2020
CompletedSeptember 1, 2020
August 1, 2020
1.9 years
November 14, 2018
August 31, 2020
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Pefusion parameters
correlation between pre-operative imaging data and histological data of Hepatocellular carcinoma
5 minutes
Secondary Outcomes (1)
Pathological examination
1 month
Study Arms (1)
perfusion computed tomography
OTHERWill be realsed before liver surgery
Interventions
Will be carried before liver surgery
Eligibility Criteria
You may qualify if:
- A diagnosis of Hepatocellular carcinoma made according to the guidelines of the American Association for the study of the Liver
- Affiliation to a national health insurance
- An indication for hepatic resection during the decision-making stage
- A request for a pre-operative Computer Tomography in our radiology unit
- An affiliation to a social security
- Informed consent given by the patient
You may not qualify if:
- Previous treatments of Hepatocellular carcinoma (medicated or surgical)
- Patient under tutorship or curatorship
- Pregnant or lactating woman
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
CHU Paul Brousse
Villejuif, 94800, France
Related Publications (1)
Lewin M, Laurent-Bellue A, Desterke C, Radu A, Feghali JA, Farah J, Agostini H, Nault JC, Vibert E, Guettier C. Evaluation of perfusion CT and dual-energy CT for predicting microvascular invasion of hepatocellular carcinoma. Abdom Radiol (NY). 2022 Jun;47(6):2115-2127. doi: 10.1007/s00261-022-03511-7. Epub 2022 Apr 13.
PMID: 35419748DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
LEWIN MAITE, MD, PhD
APHP
Central Study Contacts
DA-MOTA-FERREIRA Jean-Manuel, Radiologic
CONTACT
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- DIAGNOSTIC
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
November 14, 2018
First Posted
November 27, 2018
Study Start
January 30, 2019
Primary Completion
December 30, 2020
Study Completion
December 30, 2020
Last Updated
September 1, 2020
Record last verified: 2020-08