Key Insights

Highlights

Success Rate

78% trial completion

Published Results

164 trials with published results (9%)

Research Maturity

562 completed trials (31% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

8.6%

157 terminated out of 1826 trials

Success Rate

78.2%

-8.3% vs benchmark

Late-Stage Pipeline

11%

206 trials in Phase 3/4

Results Transparency

29%

164 of 562 completed with results

Key Signals

164 with results78% success157 terminated

Data Visualizations

Phase Distribution

1,387Total
Not Applicable (344)
Early P 1 (26)
P 1 (322)
P 2 (489)
P 3 (149)
P 4 (57)

Trial Status

Completed562
Unknown540
Recruiting296
Terminated157
Active Not Recruiting95
Withdrawn82

Trial Success Rate

78.2%

Benchmark: 86.5%

Based on 562 completed trials

Clinical Trials (1826)

Showing 20 of 20 trials
NCT01840592Phase 2Active Not RecruitingPrimary

Sorafenib Plus Doxorubicin in Patients With Advanced Hepatocellular Carcinoma With Disease Progression on Sorafenib

NCT05027425Phase 2TerminatedPrimary

Durvalumab (MEDI4736) and Tremelimumab for Hepatocellular Carcinoma in Patients Listed for a Liver Transplant

NCT07226063Phase 2Not Yet RecruitingPrimary

Maintenance Zanzalintinib and Durvalumab in Participants With Advanced Hepatocellular Cancer

NCT02908048TerminatedPrimary

Extracellular RNA Markers of Liver Disease and Cancer

NCT02968810Phase 2Active Not Recruiting

Simvastatin in Preventing Liver Cancer in Patients With Liver Cirrhosis

NCT03482102Phase 2Active Not RecruitingPrimary

Durvalumab (MEDI4736) and Tremelimumab and Radiation Therapy in Hepatocellular Carcinoma and Biliary Tract Cancer

NCT06503146Phase 2Recruiting

18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

NCT06859840Not ApplicableActive Not RecruitingPrimary

LEAF(Liver Tumor dEtection And classiFication AI)

NCT06096779Phase 2RecruitingPrimary

A Study Evaluating Atezolizumab, With or Without Bevacizumab, in Participants With Unresectable Hepatocellular Carcinoma and Child-pugh B7 and B8 Cirrhosis

NCT06902246Phase 2Recruiting

Regorafenib and Yttrium-90 Radioembolization for Unresectable Hepatocellular Carcinoma

NCT04118114Phase 2Completed

Phase II Study of PRL3-ZUMAB in Advanced Solid Tumors

NCT06261047CompletedPrimary

Radiotherapy Delays Second-line Drug Therapy for Oligo Progressive Primary Liver Cancer

NCT07558200Phase 1Not Yet Recruiting

Phase Ia/Ib Study of FXB0871 Monotherapy in Locally Advanced/Metastatic Solid Tumors

NCT06519721Not ApplicableActive Not RecruitingPrimary

Safety and Efficacy Study of Lenvatinib Combined With VIC-1911 for the Treatment of Advanced HCC

NCT04472767Phase 2RecruitingPrimary

Cabozantinib Combined With Ipilimumab/Nivolumab and TACE in Patients With Hepatocellular Carcinoma

NCT05718882Not ApplicableTerminated

Lenvatinib Plus VIC-1911 in Lenvatinib-unresponsive or Lenvatinib-resistant HCC

NCT02626312Phase 1Active Not Recruiting

Radiation Therapy in Treating Patients With Hepatocellular Carcinoma, Cholangiocarcinoma, or Liver Metastasis Who Have Impaired Liver Function

NCT06710223Phase 1RecruitingPrimary

Cryoablation and Arterial Infusion of SD-101 in Combination With Durvalumab and Tremelimumab

NCT04712643Phase 3Active Not RecruitingPrimary

A Study of TACE Combined With Atezolizumab Plus Bevacizumab or TACE Alone in Patients With Untreated Heaptocellular Carcionma

NCT05063565Phase 2Active Not RecruitingPrimary

TheraSphere With Durvalumab and Tremelimumab for HCC

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Research Network

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