Key Insights

Highlights

Success Rate

78% trial completion

Published Results

169 trials with published results (9%)

Research Maturity

577 completed trials (31% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

8.7%

161 terminated out of 1842 trials

Success Rate

78.2%

-8.4% vs benchmark

Late-Stage Pipeline

11%

208 trials in Phase 3/4

Results Transparency

29%

169 of 577 completed with results

Key Signals

169 with results78% success161 terminated

Data Visualizations

Phase Distribution

1,396Total
Not Applicable (347)
Early P 1 (27)
P 1 (324)
P 2 (490)
P 3 (151)
P 4 (57)

Trial Status

Completed577
Unknown532
Recruiting291
Terminated161
Active Not Recruiting97
Not Yet Recruiting83

Trial Success Rate

78.2%

Benchmark: 86.5%

Based on 577 completed trials

Clinical Trials (1842)

Showing 20 of 20 trials
NCT03383458Phase 3Active Not RecruitingPrimary

A Study of Nivolumab in Participants With Hepatocellular Carcinoma Who Are at High Risk of Recurrence After Curative Hepatic Resection or Ablation

NCT05063565Phase 2Active Not RecruitingPrimary

TheraSphere With Durvalumab and Tremelimumab for HCC

NCT04912765Phase 2RecruitingPrimary

Neoantigen Dendritic Cell Vaccine and Nivolumab in HCC and Liver Metastases From CRC

NCT04194775Phase 3Active Not RecruitingPrimary

A Study of Nofazinlimab (CS1003) in Subjects With Advanced Hepatocellular Carcinoma

NCT07285044Phase 2Recruiting

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

NCT07732686Not Yet Recruiting

Analysis of Breath Volatile Organic Compounds Using Mass Spectrometry

NCT05621499Not ApplicableActive Not RecruitingPrimary

HAIC or Lenvatinib Combined With Sintilimab for High Recurrence Risk Resectable Solitary Hepatocellular Carcinoma

NCT06723275Recruiting

LEOPARD Prospective Validation Cohort 1

NCT06675604Recruiting

LEOPARD Training and Validation Data Collection Study

NCT04712643Phase 3Active Not RecruitingPrimary

A Study of TACE Combined With Atezolizumab Plus Bevacizumab or TACE Alone in Patients With Untreated Heaptocellular Carcionma

NCT07479485Phase 1RecruitingPrimary

MRG006A Combination Therapy for Advanced Hepatocellular Carcinoma (Phase I/II)

NCT07059494Phase 4RecruitingPrimary

Atezolizumab and Bevacizumab in Combination With Y^90 Radioembolization in HCC for Liver Transplant

NCT02772003Phase 1Active Not Recruiting

DNA Vaccine Therapy in Treating Patients With Chronic Hepatitis C Virus Infection

NCT06710223Phase 1Active Not RecruitingPrimary

Cryoablation and Arterial Infusion of SD-101 in Combination With Durvalumab and Tremelimumab

NCT07607769RecruitingPrimary

MONTEROSA - Italian Multicenter Observational Study to Evaluate Time to Clinical Hepatic Decompensation, Quality of Life, Effectiveness, and Safety of Tremelimumab Plus Durvalumab in Patients With Advanced or Unresectable Hepatocellular Carcinoma Who Have Received no Prior Systemic Treatment.

NCT03298451Phase 3Active Not RecruitingPrimary

Study of Durvalumab and Tremelimumab as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma

NCT06910657Phase 1Recruiting

IDOV-Immune for Advanced Solid Tumors

NCT06193733Phase 2Active Not RecruitingPrimary

Dendritic Cell Vaccination to Prevent Hepatocellular Carcinoma Recurrence After Liver Resection - Phase II Clinical Trial

NCT06796114Not ApplicableRecruitingPrimary

Identification of Innovative Biomarkers to Predict Outcomes in Hepatocellular Carcinoma Treated With Tremelimumab and Durvalumab

NCT05208762Phase 1Recruiting

A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

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