Indirect Measurement of Respiratory Quotient in Coelioscopic Surgery

NCT03751579 | Withdrawn

• 1 other identifier: PI2018_843_0046
• Study Type: observational
• Target: N/A
• Locations: 0 countries
• Sites: N/A

Brief Summary

The measurement of VO2 and VCO2 makes it possible to calculate the respiratory quotient (RQ) (VCO2 / VO2) which is a reflection of human energy metabolism and therefore of anaerobiosis. A study has been conducted in our department to demonstrate the ability of the indirectly measured RQ from the inspired and exhaled breath analysis of the anesthetic respirator to predict the onset of anaerobic metabolism and postoperative complications in the operating room. But, because of artificially increase of carbon dioxide due to insufflation, coelioscopic surgery was an exclusion criteria of our pilot study. However, no study has examined the impact of coelioscopy on the indirect measurement of RQ

Conditions

Respiratory Quotient Measurement

Keywords

coelioscopic; surgery complications; respiratory quotient

Outcome Measures

Primary Outcomes (1)

• Indirect respiratory quotient by measurement of VO2 and VCO2

  The measurement of VO2 and VCO2 makes it possible to calculate the respiratory quotient (RQ) (VCO2 / VO2)

  during coelioscopic surgery

Secondary Outcomes (1)

• occurence of at least one post-operative complication

  through study completion, an average of 6 months

Interventions

coelioscopic surgery PROCEDURE

observational study based on the computation of respiratory quotient in patient cohort treated by routine coelioscopic surgery

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Inclusion Criteria: * Age\>18 years old * Adults admitted to the operating room for coelioscopic surgery Exclusion Criteria: * Cardiac and thoracic surgery * Preoperative oxygen therapy

You may qualify if:

• Age\>18 years old
• Adults admitted to the operating room for coelioscopic surgery

You may not qualify if:

• Cardiac and thoracic surgery
• Preoperative oxygen therapy

Sponsors & Collaborators

• Centre Hospitalier Universitaire, Amiens: lead

Related Publications (1)

• Bar S, Santarelli D, de Broca B, Abou Arab O, Leviel F, Miclo M, Dupont H, Guinot PG, Lorne E. Predictive value of the respiratory exchange ratio for the occurrence of postoperative complications in laparoscopic surgery: a prospective and observational study. J Clin Monit Comput. 2021 Aug;35(4):849-858. doi: 10.1007/s10877-020-00544-5. Epub 2020 Jun 12.

  PMID: 32533528 DERIVED

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 8, 2018
• First Posted: November 23, 2018
• Study Start: November 1, 2018
• Primary Completion: May 1, 2019
• Study Completion: May 1, 2019
• Last Updated: May 10, 2023

Record last verified: 2023-05