Color Doppler in Varicocelectomy in Infertile Patient

NCT03750370 | Unknown

• 1 other identifier: doppler in varicocelectomy
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

To evaluate the long-term effects of varicocelectomy on testicular arterial flow via Color Doppler Sonography Parameters; The arterial flow velocities (peak systolic velocity \[PSV\] and end diastolic velocity \[EDV\]) and the resistance indices against this flow (resistive index \[RI\] and pulsatility index \[PI\]) of the testicular artery.

Conditions

Varicocelectomy; Doppler

Outcome Measures

Primary Outcomes (1)

• Evaluate testicular perfusion before and after varicocelectomy

  Evaluation of testicular perfusion is done by Comparison between Doppler sonographic Parameters Peak systolic velocity ( Cm / sec) , End diastolic velocity ( Cm / sec) , Pulsatility index , And Resistive index Values Before and after varicocelectomy Operation.

  baseline

Interventions

Doppler ultrasound DEVICE

Colored Doppler Sonography is well established to illustrate microvascularity and therefore perfusion of the testis. The arterial flow velocities (peak systolic velocity \[PSV\] and end diastolic velocity \[EDV\]) and the resistance indices against this flow (resistive index \[RI\] and pulsatility index \[PI\]) in the testis can be measured with this technique.

Eligibility Criteria

• Sex: male
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Egyptian Population , Random Selection of 50 patients with varicocele in the waiting list of varicocelectomy either open or laparoscopic approaches

You may qualify if:

• Patients with subfertility in different age groups with either unilateral or bilateral clinical varicoceles and at least one abnormal semen parameter.

You may not qualify if:

• Patients with varicocele with normal semen parameters.
• Fertile Patients with varicoceles seeking operation only to relieve pain and heaviness.
• Patients with recurrent varicoceles after operation.

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Faculty of Medicine of Assuit

Asyut, 71515, Egypt

RECRUITING

Related Publications (3)

• Tarhan S, Ucer O, Sahin MO, Gumus B. Long-term effect of microsurgical inguinal varicocelectomy on testicular blood flow. J Androl. 2011 Jan-Feb;32(1):33-9. doi: 10.2164/jandrol.109.009977. Epub 2010 Jul 29.

  PMID: 20671143 BACKGROUND

• Zhang M, Du L, Liu Z, Qi H, Chu Q. The effects of varicocelectomy on testicular arterial blood flow: laparoscopic surgery versus microsurgery. Urol J. 2014 Nov 1;11(5):1900-6.

  PMID: 25361712 BACKGROUND

• Akand M, Koplay M, Islamoglu N, Altintas E, Kilic O, Gul M, Kulaksizoglu H, Sivri M, Goktas S. Color Doppler ultrasound characteristics after subinguinal microscopic varicocelectomy. Med Ultrason. 2017 Jan 31;19(1):59-65. doi: 10.11152/mu-920.

  PMID: 28180198 BACKGROUND

MeSH Terms

Interventions

Ultrasonography, Doppler

Intervention Hierarchy (Ancestors)

Ultrasonography; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis

Central Study Contacts

Mahmoud Mohammad Aly, M.B.B.CH

CONTACT

00201011367958; am.8892@gmail.com

Eman Abu- EL-Hamd, Professor

CONTACT

01001980793; dr.eman_08@yahoo.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident

Study Record Dates

• First Submitted: November 18, 2018
• First Posted: November 23, 2018
• Study Start: January 1, 2019
• Primary Completion: December 1, 2019
• Study Completion: April 1, 2020
• Last Updated: January 22, 2019

Record last verified: 2019-01

Locations

EG (1)