Revaluation of Wells' Clinical Prediction Score of Deep Vein Thrombosis (DVT) in Inpatients With Thromboprophylaxis Treatment

NCT03784937 | Completed

• 2 other identifiers: 1994797v02017-A02316-47
• Study Type: observational
• Target: 415
• Locations: 1 country
• Sites: 1

Brief Summary

This study aimed (1) revaluating the efficacy of the Wells' clinical prediction score for an inpatient population; and the weight of the presence of thromboprophylaxis treatment on the score, and (2) evaluating the correlation of a risk stratification established between a physician specialised in thrombosis and any other doctor.

Conditions

Deep Vein Thrombosis; Thromboses, Venous

Keywords

Wells Clinical score; Thromboprophylaxis

Outcome Measures

Primary Outcomes (1)

• Performance of the Wells Clinical prediction score

  Analyse area under the curve (AUC) of the Wells' score ROC (Receiver Operating Characteristic) curve for an inpatient population

  For enrollment to end of enrollment at 12 months

Secondary Outcomes (2)

• Impact of thromboprophylaxis treatment

  For enrollment to end of enrollment at 12 months

• Coherency of Wells' score between an doctor specialized in thrombosis and any other doctor.

  For enrollment to end of enrollment at 12 months

Interventions

Doppler ultrasound DIAGNOSTIC_TEST

Each patient received Doppler ultrasound for research of DVT, no matter the risk stratification.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Any patient adressed to an Vascular Medicine unit for a clinical suspicion of DVT, with risk stratification throught the modified Wells score by the referent doctor.

You may qualify if:

• Any patient addressed to an Vascular Medicine unit for a clinical suspicion of DVT, with risk stratification through the modified Wells score by the referent doctor.

You may not qualify if:

• Patient addressed to our Vascular Medicine unit for any other reason.
• Patient addressed to our Vascular Medicine unit for DVT detection to help in a pulmonary embolism suspicion.
• Age under 18 yo
• Patients unable to express their informed consent.

Sponsors & Collaborators

• Centre Hospitalier Universitaire de Nīmes: lead

Study Sites (1)

Centre Hospitalo-Universitaire de Nîmes

Nîmes, 30000, France

Location

Related Publications (1)

• Trihan JE, Adam M, Jidal S, Aichoun I, Coudray S, Laurent J, Chaussavoine L, Chausserie S, Guillaumat J, Laneelle D, Perez-Martin A. Performance of the Wells score in predicting deep vein thrombosis in medical and surgical hospitalized patients with or without thromboprophylaxis: The R-WITT study. Vasc Med. 2021 Jun;26(3):288-296. doi: 10.1177/1358863X21994672. Epub 2021 Mar 22.

  PMID: 33749393 RESULT

MeSH Terms

Conditions

Venous Thrombosis

Interventions

Ultrasonography, Doppler

Condition Hierarchy (Ancestors)

Thrombosis; Embolism and Thrombosis; Vascular Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Ultrasonography; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 7, 2018
• First Posted: December 24, 2018
• Study Start: February 1, 2018
• Primary Completion: March 4, 2019
• Study Completion: March 4, 2019
• Last Updated: December 1, 2025

Record last verified: 2018-12

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)