NCT03727997

Brief Summary

Acute kidney injury is associated with increased short-term and long-term morbidity and mortality. Long-term data is lacking in low to middle-income countries. Our study aims to follow the acute kidney injury patients stage 3 in intensive care units for 2 years to observe mortality and associated factors.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,315

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Apr 2019

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 26, 2018

Completed
6 days until next milestone

First Posted

Study publicly available on registry

November 1, 2018

Completed
5 months until next milestone

Study Start

First participant enrolled

April 1, 2019

Completed
3.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2022

Completed
2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2024

Completed
Last Updated

August 3, 2025

Status Verified

July 1, 2025

Enrollment Period

3.7 years

First QC Date

October 26, 2018

Last Update Submit

July 30, 2025

Conditions

Acute Kidney Injury

Keywords

Acute kidney injuryRenal replacement therapyIntensive Care Unit

Outcome Measures

Primary Outcomes (1)

  • 2-year mortality

    2-year

Secondary Outcomes (4)

  • Hospital mortality

    28-day

  • RRT rate

    28-day

  • Renal recovery

    28-day

  • 2-year major adverse kidney events

    2-year

Study Arms (1)

AKI patients stage 3

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients who are admitted in intensive care units who are diagnosed with acute kidney injury by KDIGO criteria (cr or urine output criteria) stage 3

You may qualify if:

  • AKI stage 3
  • At least 18 years old

You may not qualify if:

  • ESRD patients (eGFR \< 15 mL/min/1.73 m2)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Medicine, Chulalongkorn University

Bangkok, Pathumwan, 10330, Thailand

Location

MeSH Terms

Conditions

Acute Kidney Injury

Condition Hierarchy (Ancestors)

Renal InsufficiencyKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Faculty of Medicine

Study Record Dates

First Submitted

October 26, 2018

First Posted

November 1, 2018

Study Start

April 1, 2019

Primary Completion

December 1, 2022

Study Completion

December 1, 2024

Last Updated

August 3, 2025

Record last verified: 2025-07

Data Sharing

IPD Sharing
Will not share

Locations

TH(1)