Sprint Interval Training During Rehabilitation After Spinal Cord Injury

NCT03709095 | Completed

• 1 other identifier: SprintSCI
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

Immediately following a spinal cord injury (SCI), patients are admitted to inpatient rehabilitation where they undergo physical reconditioning in preparation for a return to home setting. The current standard of practice for aerobic training is performing arm-ergometry for 25 mins at a frequency of three times per week. Given the move towards shortened length of stay during inpatient rehabilitation, performing MICT can consume a considerable amount of therapy time. Sprint interval training (SIT) has been shown to elicit similar improvements in physical capacity, despite a reduced time commitment to MICT. However, there are no controlled trials comparing the effects of SIT to MICT in individuals with SCI undergoing inpatient rehabilitation. The primary aim of this study was to investigate the efficacy of a five-week, thrice weekly 10 min SIT program and compare outcome measures to a traditional 25 minute MICT program on the arm-ergometer in individuals with SCI undergoing inpatient clinical rehabilitation. It was hypothesized that five weeks of SIT and MICT would induce similar changes in maximal and sub-maximal exercise performance, self-efficacy for exercise, and exercise enjoyment, despite large differences in training volume and time commitment. It was also hypothesized that SIT would be well tolerated and elicit higher levels of cardiovascular strain than MICT.

Conditions

Spinal Cord Injuries; Rehabilitation; Exercise

Keywords

Inpatient Rehabilitation; Sprint interval training; Exercise; Spinal Cord Injury

Outcome Measures

Primary Outcomes (2)

• Change in peak power output

  maximum amount of power produced during a graded exercise test on the arm-ergometer

  Change in peak power output from baseline to 5 weeks

• Change in sub-maximal arm-ergometry

  Participants performed three 5-minute steady state workloads on the arm-ergometer at power outputs corresponding to RPE's of 8, 10 and 12. Participants were given a minimum of 2 minutes, and a maximum of 5 minutes of rest in between each workload.

  Change in sub-maximal arm-ergometry from baseline to 5 weeks

Secondary Outcomes (5)

• Cardiovascular Responses

  Throughout each week of training (Week 1,Week 2, Week 3, Week4, Week 5)

• Perceptual Responses

  Throughout each week of training (Week 1,Week 2, Week 3, Week4, Week 5)

• Change in self-efficacy for exercise

  Change in self-efficacy from baseline to 5 weeks

• Exercise Satisfaction

  Measured only at the end of the intervention (5 weeks)

• Pain perceptions

  Measured only at the end of the intervention (5 weeks)

Study Arms (2)

Moderate Intensity Continuous Training

ACTIVE COMPARATOR

Training was performed three times a week for five weeks. Each session began with a 2 minute warm up, and concluded with a 3 minute cool down. Following the warm-up, participants performed 20 minutes of arm cycling at a self-selected cadence at 45-65% of their peak power output. Total training duration was 25 mins.

Other: moderate intensity continuous training

Sprint Interval Training

EXPERIMENTAL

The SIT protocol was adopted from Gillen and colleagues (See Ref), and consisted of 3 x 20 second "all-out" efforts at ≥ 100% of an individuals peak power output. Each sprint was interspersed by 120 seconds of active recovery at 10% of an individuals peak power output. Total training duration was 10 mins.

Other: Sprint interval training

Interventions

Sprint interval training OTHER

Participants utilized the arm ergometer for improving aerobic exercise capacity

Sprint Interval Training

moderate intensity continuous training OTHER

Participants utilized the arm ergometer for improving aerobic exercise capacity

Moderate Intensity Continuous Training

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Participants with sub-acute spinal cord injury (time since injury: 14 - 182 days)
• Undergoing inpatient rehabilitation
• Aged 18-65 years
• Injury level at the second cervical vertebrae (C2) or below

You may not qualify if:

• \- Unable to perform arm-ergometry training

Sponsors & Collaborators

• McMaster University: lead
• Hamilton Health Sciences Corporation: collaborator

Study Sites (1)

McMaster University

Hamilton, Ontario, L8S 4L8, Canada

Location

Related Publications (4)

• Gillen JB, Martin BJ, MacInnis MJ, Skelly LE, Tarnopolsky MA, Gibala MJ. Twelve Weeks of Sprint Interval Training Improves Indices of Cardiometabolic Health Similar to Traditional Endurance Training despite a Five-Fold Lower Exercise Volume and Time Commitment. PLoS One. 2016 Apr 26;11(4):e0154075. doi: 10.1371/journal.pone.0154075. eCollection 2016.

  PMID: 27115137 BACKGROUND

• Hicks AL, Martin KA, Ditor DS, Latimer AE, Craven C, Bugaresti J, McCartney N. Long-term exercise training in persons with spinal cord injury: effects on strength, arm ergometry performance and psychological well-being. Spinal Cord. 2003 Jan;41(1):34-43. doi: 10.1038/sj.sc.3101389.

  PMID: 12494319 BACKGROUND

• Nightingale TE, Metcalfe RS, Vollaard NB, Bilzon JL. Exercise Guidelines to Promote Cardiometabolic Health in Spinal Cord Injured Humans: Time to Raise the Intensity? Arch Phys Med Rehabil. 2017 Aug;98(8):1693-1704. doi: 10.1016/j.apmr.2016.12.008. Epub 2017 Jan 13.

  PMID: 28089898 BACKGROUND

• Astorino TA, Thum JS. Within-session responses to high-intensity interval training in spinal cord injury. Disabil Rehabil. 2018 Feb;40(4):444-449. doi: 10.1080/09638288.2016.1260648. Epub 2016 Dec 8.

  PMID: 27930890 BACKGROUND

MeSH Terms

Conditions

Spinal Cord Injuries; Motor Activity

Interventions

High-Intensity Interval Training

Condition Hierarchy (Ancestors)

Spinal Cord Diseases; Central Nervous System Diseases; Nervous System Diseases; Trauma, Nervous System; Wounds and Injuries; Behavior

Intervention Hierarchy (Ancestors)

Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Audrey L Hicks, PhD

  McMaster University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Participants were randomized to one of two groups: (A) sprint interval training (SIT) or (B) moderate intensity continuous training (MICT).

Study Record Dates

• First Submitted: October 11, 2018
• First Posted: October 17, 2018
• Study Start: June 1, 2017
• Primary Completion: June 1, 2018
• Study Completion: June 1, 2018
• Last Updated: October 17, 2018

Record last verified: 2018-10

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)