Comparison of Environmental Factors Between the Areas of Over- and Under-incidence of Crohn's Disease in the Haut de France Region, by the Study of Dental Exposomes
EXPOSOMES
2 other identifiers
observational
14
1 country
1
Brief Summary
the aim of this preliminary observational study is to compare external exposomes from 10 teeth issued through 10 subjects living in high incidence of crohn's disease area and 10 teeth issued through 10 subjects living in low incidence of crohn's disease area.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Apr 2019
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 11, 2018
CompletedFirst Posted
Study publicly available on registry
October 15, 2018
CompletedStudy Start
First participant enrolled
April 2, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 16, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
July 16, 2019
CompletedDecember 26, 2025
December 1, 2025
4 months
October 11, 2018
December 18, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
comparison of aluminum rate using metabolomic method in teeth between subjects living in high and low incidence crohn's disease areas.
Baseline: one session
Secondary Outcomes (1)
comparison of environmental exposomes using metabolomic method in teeth between subjects living in high and low incidence crohn's disease areas.
Baseline: one session
Study Arms (2)
high incidence crohn's disease area
subjects living in high incidence crohn's disease area coming in dentist for dental extraction linked to medical indication
low incidence crohn's disease area
subjects living in low incidence crohn's disease area coming in dentist for dental extractionlinked to medical indication
Eligibility Criteria
adults subjects living in high and low incidence of crohn's disease areas and needing a dental extraction for medical indication.
You may qualify if:
- adults subjects living in high and low incidence of crohn's disease areas and needing a dental extraction for medical indication
You may not qualify if:
- smokers during 10 last years
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
CHU lille
Lille, 59037, France
Study Officials
- PRINCIPAL INVESTIGATOR
Corinne GOWER, MD,PhD
University Hospital, Lille
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
October 11, 2018
First Posted
October 15, 2018
Study Start
April 2, 2019
Primary Completion
July 16, 2019
Study Completion
July 16, 2019
Last Updated
December 26, 2025
Record last verified: 2025-12