NCT03694743

Brief Summary

Pain after endodontic treatment is considered the most disturbing problem facing both the patient and the dentist especially in cases of symptomatic pulpitis as the patient is expecting to relief the pain that already exists.Therefore, this study aims to find a solution for the post-operative pain felt by the patient with symptomatic pulpitis in mandibular molars through comparing post-operative pain following use of 2Shape and Protaper Next rotary systems.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
44

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Dec 2018

Typical duration for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 29, 2018

Completed
4 days until next milestone

First Posted

Study publicly available on registry

October 3, 2018

Completed
2 months until next milestone

Study Start

First participant enrolled

December 1, 2018

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2020

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2020

Completed
Last Updated

October 3, 2018

Status Verified

September 1, 2018

Enrollment Period

1.7 years

First QC Date

September 29, 2018

Last Update Submit

October 1, 2018

Conditions

Keywords

mandibular molars

Outcome Measures

Primary Outcomes (1)

  • intensity of postoperative pain assessed by numerical rating scale Immediately after the end of treatment, and at 6, 12, 24, 48, and 72 hours. post-operative pain

    using numerical rating scale ranges between (0-10) where 0 indicates no pain while 10 indicates maximum pain degree

    3 days

Secondary Outcomes (1)

  • Need for / and number of analgesic tablets taken.

    3 days

Other Outcomes (1)

  • incidence of instrument seperation during endodontic treatment (instrument seperation means instrument fracture)

    1 day

Study Arms (2)

2Shape rotary system

EXPERIMENTAL

root canal preparation using 2Shape rotary system in mandibular molars with symptomatic pulpitis

Device: 2Shape rotary system

Protaper Next rotary system

ACTIVE COMPARATOR

root canal preparation using Protaper Next rotary system comparing to 2Shape rotary system in mandibular molars with symptomatic pulpitis

Device: 2Shape rotary system

Interventions

root canal preparation

2Shape rotary systemProtaper Next rotary system

Eligibility Criteria

Age22 Years - 45 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • \- Medically free patients.
  • Patients with symptomatic pulpitis in one of their mandibular molars.
  • Patient's age ranges between 22 to 45 years with no sex predilection.
  • Patients who can understand Numerical Analogue Scales (NRS).
  • Patients able to sign informed consent.

You may not qualify if:

  • \- Patients having a systemic disorder.
  • Presence of periapical lesion.
  • Pregnant females.
  • Patients who had taken analgesics during the last 12 hours preoperatively.
  • Patients having active pain in more than one tooth.
  • Non- educated patients.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Pulpitis

Condition Hierarchy (Ancestors)

Dental Pulp DiseasesTooth DiseasesStomatognathic Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Masking Details
Double (Participant, Outcomes Assessor)
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Ass.lecturer of endodotics

Study Record Dates

First Submitted

September 29, 2018

First Posted

October 3, 2018

Study Start

December 1, 2018

Primary Completion

August 1, 2020

Study Completion

October 1, 2020

Last Updated

October 3, 2018

Record last verified: 2018-09