NCT03679221|Unknown
Motoric Cognitive Risk and Depression
The Association of Depression With "Motoric Cognitive Risk" Syndrome in the Canadian Population
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The Association of Depression With "Motoric Cognitive Risk" Syndrome in the Canadian Population
Sponsor study identifier
observational
30,000
1 country
1
Study Start
July 24, 2019
Actual (reported)Primary Completion
October 31, 2024
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
December 1, 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
The overall objective of the proposal is to examine the association between depression and the newly reported "motoric cognitive risk" (MCR) syndrome, which is a pre-dementia syndrome combining subjective cognitive complaint (i.e.; memory complaint) with objective slow gait speed, in the Canadian population, with the baseline assessment of the Canadian Longitudinal Study on Aging (CLSA). The Canadian and global population are continuously aging. Moreover, the number of individuals affected by dementia is on the rise. One good predictor of dementia is Motoric Cognitive Risk (MCR) syndrome. MCR syndrome is a highly prevalent, newly defined syndrome that combines slow gait and subjective cognitive complaint. Depression is also highly prevalent in the older population and can affect both cognition and gait. Thus, an overlap between MCR and depression is possible. Yet few studies have examined the association between MCR and depression, thus emphasizing the importance of further investigating this association. This project encompasses determining the association of MCR syndrome with depression in the Canadian context as a step to better understand MCR syndrome in Canada.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 1, 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
September 18, 2018
Actual (reported)September 20, 2018
Actual (reported)July 24, 2019
Actual (reported)October 31, 2024
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
December 1, 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Subjective cognitive complaint
elicited from the 60-minute interview telephone questionnaire item Chronic Conditions Tracking (CTT\_19 CCT\_MEMPB\_TRM) done in CLSA study
1 hour
Slow gait speed
1 day
divided in two subgroups: individuals with and without cardio-vascular risk factors and diseases
divided in two subgroups: individuals with and without cardio-vascular risk factors and diseases
divided in two subgroups: individuals with and without cardio-vascular risk factors and diseases
divided in two subgroups: individuals with and without cardio-vascular risk factors and diseases
telephone interview questionnaire, in-home face-to-face interview, and data from the Collection Site
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Individuals eligible for this study will be the participants of the CLSA
Jewish General Hospital
Montreal, Quebec, H3T 1E2, Canada
Olivier Beauchet, MD
Jewish General Hospital
First Submitted
September 18, 2018
First Posted
September 20, 2018
Study Start
July 24, 2019
Actual (reported)Primary Completion
October 31, 2024
Estimated (date passed)Multimodal Identification of Depressive Symptoms in the Elderly
Contact the study team to confirm eligibility.
This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
December 1, 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Last Updated
February 23, 2024
Record last verified: 2024-02
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Source: ClinicalTrials.gov.
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