Multimodal Identification of Depressive Symptoms in the Elderly

NCT07112118 | Not Yet Recruiting DMC

• 2 other identifiers: KY2025.0115.0172404094
• Study Type: observational
• Target: 2,000
• Locations: 1 country
• Sites: 1

Brief Summary

Screening with depression scales alone is subjective, and relying on single-modal data often leads to incomplete identification of symptoms that are easily missed or misdiagnosed. In this study, we first aim to use artificial intelligence to construct a depression symptom recognition model, concatenate multimodal features such as facial expression, audio, text, and postural behavior, and deeply fuse them to construct a multimodal model.

Conditions

Depression

Keywords

depression symptoms

Outcome Measures

Primary Outcomes (1)

• Use the PHQ-9 (Patient Health Questionnaire - 9 ) to assess whether the respondents have depressive symptoms. The scale score is one point for each item.

  If the PHQ-9 score is 5 or higher, it is determined as a positive sign of depressive symptoms.

  2025.09.01-2026.09.01

Study Arms (2)

non-depression

Elderly people without depressive symptoms

Other: data collection

depression

Elderly people at risk of depression

Other: data collection

Interventions

data collection OTHER

Collect the facial expressions, audio, text and postural behavior data of the respondents using electronic devices.

depression; non-depression

Eligibility Criteria

• Age: 60 Years - 100 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Elderly individuals aged 60 years or older

You may qualify if:

• Elderly individuals aged 60 years or older.
• Residents of the community (with residence time of more than 6 months).
• Possessing certain reading, writing and comprehension skills, being able to communicate with researchers without obstacles, and being able to independently complete the measurement of various indicators or, although unable to independently fill out the questionnaire, being able to independently make evaluations of the questionnaire items.
• Those who have given informed consent.

You may not qualify if:

• Those who meet the diagnostic criteria for cognitive impairment (dementia) as stipulated in DSM-5, and/or who suffer from severe physical diseases (such as advanced cancer, cardiovascular and cerebrovascular diseases, etc.).
• Those who are undergoing antidepressant treatment.
• Elderly individuals who have had suicidal thoughts in any psychological assessment, should be referred to the psychological hotline platform in Wuhan.

Sponsors & Collaborators

• Wuhan Mental Health Centre: lead

Study Sites (1)

Wuhan Mental Health Center

Wuhan, Hubei, 430012, China

Location

MeSH Terms

Conditions

Depression

Interventions

Data Collection

Condition Hierarchy (Ancestors)

Behavioral Symptoms; Behavior

Intervention Hierarchy (Ancestors)

Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Xiaoxv Yin, PhD

  Huazhong University of Science and Technology

  STUDY CHAIR

Central Study Contacts

Xiuxiu Zhou, PhD

CONTACT

86+13545075638; xiuxiuzhou@hust.edu.cn

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 17, 2025
• First Posted: August 8, 2025
• Study Start: September 1, 2025
• Primary Completion (Estimated): September 1, 2026
• Study Completion (Estimated): December 30, 2027
• Last Updated: August 11, 2025

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)