Risk Factors for Falls and Neurocognitive Disorders CLSA

NCT03628768 | Active Not Recruiting

• 1 other identifier: 2019-1453
• Study Type: observational
• Target: 12,000
• Locations: 1 country
• Sites: 1

Brief Summary

The study evaluates the association between the neurocognitive decline and falls.

Conditions

Neurocognitive Disorders; Geriatrics

Outcome Measures

Primary Outcomes (1)

• Fall-related injury

  Fall-related injury is an event which results in a person coming to rest accidentally on the ground or floor. If participants report having had at least one injury during the past 12 month, they will be asked to answer additional questions that are related to the consequence of fall injury.

  around 12 months

Secondary Outcomes (1)

• Medication

  around 12 months

Study Arms (6)

Healthy / Non fallers

Older cognitively healthy individuals Non fallers

Other: Data collection

Healthy / Fallers without injuries

Older cognitively healthy individuals Fallers without injuries

Other: Data collection

Healthy / Fallers with injuries

Older cognitively healthy individuals Fallers with injuries

Other: Data collection

MCI / Non fallers

Older individuals with MCI and mild dementia Non fallers

Other: Data collection

MCI / Fallers without injury

Older individuals with MCI and mild dementia Fallers without injuries

Other: Data collection

MCI / Fallers with injury

Older individuals with MCI and mild dementia Fallers with injuries

Other: Data collection

Interventions

Data collection OTHER

telephone interview questionnaire, in-home face-to-face interview, and data from the Collection Site

Healthy / Fallers with injuries; Healthy / Fallers without injuries; Healthy / Non fallers; MCI / Fallers with injury; MCI / Fallers without injury; MCI / Non fallers

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Individuals eligible for this study will be the participants of the CLSA

You may qualify if:

• Age ≥ 65 and
• Participants of the Comprehensive CLSA (i.e., individuals who participated in a 90-minute in-home face-to-face interview, and a visit to one of 11 Data Collection Sites across Canada where they took part in a range of physical assessments).

You may not qualify if:

• A fall resulting from acute medical events and/or external force,
• Moderate to severe dementia (estimated from performance on cognitive tests and scores of the Activity of Daily Living (ADL) and Instrumental Activity Daily Living (IADL) scales. Abnormal scores will be defined as 2 Standard Deviations (SDs) or more below the normal score of all cognitive tests associated with scores of ADL (/6) \<3 and a score of IADL (/8) \<4)

Sponsors & Collaborators

• Jewish General Hospital: lead

Study Sites (1)

Jewish General Hospital

Montreal, Quebec, H3T 1E2, Canada

Location

MeSH Terms

Conditions

Neurocognitive Disorders

Interventions

Data Collection

Condition Hierarchy (Ancestors)

Mental Disorders

Intervention Hierarchy (Ancestors)

Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Olivier Beauchet, MD

  Jewish General Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Target Duration: 12 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of Geriatrics

Study Record Dates

• First Submitted: August 9, 2018
• First Posted: August 14, 2018
• Study Start: July 23, 2019
• Primary Completion: July 1, 2025
• Study Completion: February 1, 2026
• Last Updated: September 19, 2024

Record last verified: 2024-09

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)