Hearing Study: Sensitivity to Features of Speech Sounds
Auditory Processing of Complex Sounds - Sensitivity to Chirps
2 other identifiers
interventional
67
1 country
1
Brief Summary
The purpose of this study is to better understand the sensitivity of listeners to the fast changes in frequency or amplitude of sounds that occur in speech. The investigators are studying ways to manipulate these aspects of sounds in an effort to make speech sounds more clear.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Jun 2020
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 8, 2018
CompletedFirst Posted
Study publicly available on registry
September 12, 2018
CompletedStudy Start
First participant enrolled
June 9, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2024
CompletedResults Posted
Study results publicly available
May 29, 2025
CompletedMay 29, 2025
May 1, 2025
4.1 years
September 8, 2018
October 15, 2024
May 9, 2025
Conditions
Outcome Measures
Primary Outcomes (3)
Pure-tone Average Thresholds
Hearing thresholds, average across test frequencies from 250 to 4000 Hz and averaged across the two ears.
6 months
F1 Discrimination Threshold
Discrimination threshold for changes in F1, the low-frequency formant (spectral peak) in the synthetic vowel sounds.
6 months
F2 Discrimination Threshold
Discrimination thresholds in % frequency for F2, the higher-frequency peak in synthetic vowel stimuli.
6 month
Study Arms (3)
Normal Hearing
ACTIVE COMPARATORSignal processing to improve intelligibility
Mild hearing loss
ACTIVE COMPARATORSignal processing to improve intelligibility
Moderate hearing loss
ACTIVE COMPARATORSignal processing to improve intelligibility
Interventions
Signal processing will be used to manipulate frequency and amplitude fluctuations in complex sounds.
Eligibility Criteria
You may qualify if:
- Normal hearing, mild or moderate symmetric sensorineural hearing loss.
You may not qualify if:
- Asymmetric hearing thresholds (more than 15 decibels (dB) threshold difference between the two ears at any frequency up to 4 kHz).
- Severe hearing loss (greater than 60 dB hearing thresholds at any frequency up to 4 kHz).
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Rochester
Rochester, New York, 14642, United States
Related Publications (1)
Carney LH, Cameron DA, Kinast KB, Feld CE, Schwarz DM, Leong UC, McDonough JM. Effects of sensorineural hearing loss on formant-frequency discrimination: Measurements and models. Hear Res. 2023 Aug;435:108788. doi: 10.1016/j.heares.2023.108788. Epub 2023 May 8.
PMID: 37224720RESULT
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Results Point of Contact
- Title
- Dr. Laurel H. Carney
- Organization
- University of Rochester
Study Officials
- PRINCIPAL INVESTIGATOR
Laurel H Carney, PhD
University of Rochester
Publication Agreements
- PI is Sponsor Employee
- Yes
- Restrictive Agreement
- No
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- BASIC SCIENCE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
September 8, 2018
First Posted
September 12, 2018
Study Start
June 9, 2020
Primary Completion
August 1, 2024
Study Completion
August 1, 2024
Last Updated
May 29, 2025
Results First Posted
May 29, 2025
Record last verified: 2025-05
Data Sharing
- IPD Sharing
- Will not share