NCT03648775

Brief Summary

HIP50 is a national, multicentre, prospective, observational study, in patients presenting a first low energy per trochanteric hip fracture on one side and treated with Y-STRUT® device implanted on the contralateral proximal femur as percutaneous internal fixation to prevent contralateral hip fracture in case of osteoporosis. The primary objective of this study is to evaluate the clinical efficacy of the studied medical device by measuring the frequency of patient with a fracture at the implantation site within 1 year after implantation. A total of 50 patients from France will be enrolled (until December 2020) and followed up to 24 months.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Dec 2017

Typical duration for all trials

Geographic Reach
1 country

5 active sites

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 6, 2017

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

August 21, 2018

Completed
6 days until next milestone

First Posted

Study publicly available on registry

August 27, 2018

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 24, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 24, 2020

Completed
Last Updated

April 29, 2020

Status Verified

April 1, 2020

Enrollment Period

2.3 years

First QC Date

August 21, 2018

Last Update Submit

April 27, 2020

Conditions

Keywords

OsteosynthesisProphylactic consolidationProximal femur

Outcome Measures

Primary Outcomes (1)

  • Frequency of post-operative fracture [Clinical efficacy of the device]

    Frequency of Y-STRUT® implanted patients with a fracture at the implantation site

    At 12 months

Secondary Outcomes (8)

  • Frequency of post-operative fracture [Clinical efficacy of the device]

    At 3 and 24 months

  • Recording of concomitants treatments [safety and feasibility of the device]

    At 3, 12 and 24 months

  • Pain [safety and feasibility of the device]

    At 3, 12 and 24 months

  • Walking conditions [safety and feasibility of the device]

    At 3, 12 and 24 months

  • Recording of adverse events and device effects [safety and feasibility of the device]

    At 3, 12 and 24 months

  • +3 more secondary outcomes

Interventions

The studied medical device consists of two components implanted in the proximal femur, combined with bone cement.

Eligibility Criteria

Age60 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients presenting a first low energy per trochanteric hip fracture on one side and treated with Y-STRUT® device implanted on the contralateral proximal femur as percutaneous internal fixation.

You may qualify if:

  • Patient of 60 years and older, according to CE indication;
  • Patient with information form signed to participate in the study;
  • Patients presenting a first low energy hip fracture on one side and having a Y-STRUT® device implanted on the contralateral hip between 0 and 120 days after the treatment of the fracture of the first hip;

You may not qualify if:

  • Patient who refuse to participate to this study;
  • Patient implanted with Y-STRUT® for another indication;
  • Patient already enrolled in a clinical study, excluding his participation to HIP50.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

Hôpital Privé d'Ambérieu

Ambérieu-en-Bugey, 01500, France

Location

Hôpital Antoine Béclère

Clamart, 92140, France

Location

Centre Hospitalier Universitaire Grenoble Alpes

La Tronche, 38700, France

Location

Centre Hospitalier Régional Orléans

Orléans, 45100, France

Location

Nouvelle Clinique de Tours Plus St Gatien

Tours, 37000, France

Location

MeSH Terms

Conditions

Hip FracturesOsteoporosis

Condition Hierarchy (Ancestors)

Femoral FracturesFractures, BoneWounds and InjuriesHip InjuriesLeg InjuriesBone Diseases, MetabolicBone DiseasesMusculoskeletal DiseasesMetabolic DiseasesNutritional and Metabolic Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 21, 2018

First Posted

August 27, 2018

Study Start

December 6, 2017

Primary Completion

March 24, 2020

Study Completion

March 24, 2020

Last Updated

April 29, 2020

Record last verified: 2020-04

Locations