The Effect of Periodontal Disease Treatment in Patients With Kidney Disease

NCT03648723 | Completed

• 1 other identifier: Ztasdemir
• Study Type: observational
• Target: 43
• Locations: 0 countries
• Sites: N/A

Brief Summary

the purpose of the present study was to compare the effects of non-surgical periodontal therapy by clinical and biochemical parameters on patients undergoing continous ambulatory peritoneal dialysis(CAPD) due to diabetic nephropathy and non-diabetic

Conditions

Periodontal Diseases

Outcome Measures

Primary Outcomes (1)

• Periodontal disease parameters change

  pocket depth (mm) evaluation .was performed by periodontal probe.

  Examinations were performed at baseline and repeated 6 months following periodontal treatment. Change is determined with at baseline - at 6 months after periodontal treatment.

Secondary Outcomes (1)

• Biochemical parameters change

  biochemical parameters were evaluated at baseline and 6 months following periodontal treatment . Change is determined with baseline - 6 months after periodontal treatment.

Study Arms (2)

Diabetic nephropathy

Diabetic nephropathy is defined by macroalbuminuria that is, a urinary albumin excretion of more than 300 mg in a 24-hour collection or macroalbuminuria and abnormal renal function as represented by an abnormality in serum creatinine, or glomerular filtration rate(GFR)

Non-diabetic nephropathy

This group consisted of diagnosis with nephropathy without diabetes mellitus.

Eligibility Criteria

• Age: 31 Years - 65 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

All patients in each groups had to have chronic periodontitis and ≥15 natural teeth; moreover, they needed to be \>30 years old. History of antibiotic or anti-inflammatory drugs within the previous 6 months, pregnancy or lactation, periodontal therapy within 6 months prior to the study, past or current smoking and alcohol consumption were considered to be exclusion criteria.

You may qualify if:

• had to have chronic periodontitis
• ≥15 natural teeth
• needed to be \>30 years old

You may not qualify if:

• History of antibiotic or anti-inflammatory drugs within the previous 6 months
• pregnancy or lactation
• periodontal therapy within 6 months prior to the study
• past or current smoking and alcohol consumption

Sponsors & Collaborators

• TC Erciyes University: lead

MeSH Terms

Conditions

Periodontal Diseases

Condition Hierarchy (Ancestors)

Mouth Diseases; Stomatognathic Diseases

Study Officials

• Zekeriya Taşdemir

  TC Erciyes University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: August 22, 2018
• First Posted: August 27, 2018
• Study Start: January 10, 2016
• Primary Completion: January 10, 2017
• Study Completion: May 10, 2017
• Last Updated: August 27, 2018

Record last verified: 2018-08