The Acute Effect of Physical Activity on Blood Glucose in Pregnant Women
1 other identifier
interventional
15
1 country
1
Brief Summary
The aim of the project is to investigate the acute effect of exercise on blood glucose after glucose consumption. Thereby we wish to achieve knowledge that can improve prevention and treatment of gestational overweight and gestational diabetes mellitus (GDM). This will prevent serious complications during pregnancy and birth, but also long term complications like type 2 diabetes mellitus (T2DM) for both the mother and the offspring. 15 pregnant participants will perform two Oral Glucose Tolerance Tests (OGTT). One is followed by physical activity and the other is followed by inactivity and will serve as control. Blood glucose will be monitored continuously during the study.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Aug 2017
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 21, 2017
CompletedFirst Submitted
Initial submission to the registry
April 9, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 27, 2018
CompletedFirst Posted
Study publicly available on registry
August 23, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
August 30, 2018
CompletedMay 6, 2019
May 1, 2019
11 months
April 9, 2018
May 3, 2019
Conditions
Outcome Measures
Primary Outcomes (1)
Blood glucose
Difference in blood glucose between experimental intervention and control intervention.
Through intervention periods of 2 hours.
Study Arms (2)
Experimental intervention
EXPERIMENTALOral Glucose Tolerance Test and physical activity
Control intervention
OTHEROral Glucose Tolerance Test and inactivity.
Interventions
75g of glucose is consumed
20 minutes of fixed intensity exercise on a bicycle ergometer.
Eligibility Criteria
You may qualify if:
- Prepregnancy BMI \> 27
You may not qualify if:
- Physical disability that affect movement
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Department of Obstetrics and Gynecology, Aarhus University Hospital
Aarhus, 8200, Denmark
Related Publications (1)
Andersen MB, Ovesen PG, Daugaard M, Ostenfeld EB, Fuglsang J. Cycling reduces blood glucose excursions after an oral glucose tolerance test in pregnant women: a randomized crossover trial. Appl Physiol Nutr Metab. 2020 Nov;45(11):1247-1252. doi: 10.1139/apnm-2020-0020. Epub 2020 May 22.
PMID: 32442384DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Per Ovesen, MD, Prof.
Aarhus University Hospital / University of Aarhus
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 9, 2018
First Posted
August 23, 2018
Study Start
August 21, 2017
Primary Completion
July 27, 2018
Study Completion
August 30, 2018
Last Updated
May 6, 2019
Record last verified: 2019-05
Data Sharing
- IPD Sharing
- Will not share