The Acute Effect of Physical Activity on Postprandial Blood Glucose in Pregnant Women

NCT03641170 | Completed DMC

• 1 other identifier: Diet study
• Study Type: interventional
• Target: 18
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the project is to investigate the acute effect of exercise on blood glucose after food consumption. Thereby the investigators wish to achieve knowledge that can improve prevention and treatment of gestational overweight and gestational diabetes mellitus (GDM). This will prevent serious complications during pregnancy and birth, but also long term complications like type 2 diabetes mellitus (T2DM) for both the mother and the offspring. Inclusion will be 60 pregnant women divided into three groups - normal weight, overweight and obese and women with gestational diabetes. Participants will receive a fixed diet and go through an intervention period with physical activity immediately after each main meal and a control period with inactivity after the meals. Blood glucose will be the main outcome.

Conditions

Gestational Diabetes

Outcome Measures

Primary Outcomes (1)

• Blood glucose

  Differences in blood glucose between experimental intervention (physical activity) and control intervention (inactivity).

  Through intervention periods of 4 days.

Study Arms (2)

Experimental intervention

EXPERIMENTAL

Fixed diet and physical activity.

Behavioral: Physical activity; Other: Fixed diet.

Control intervention

OTHER

Fixed diet and inactivity.

Behavioral: Inactivity; Other: Fixed diet.

Interventions

Physical activity BEHAVIORAL

Interval walking performed after each main meal.

Experimental intervention

Inactivity BEHAVIORAL

Inactivity after each main meal.

Control intervention

Fixed diet. OTHER

Participants will receive a fixed diet through out the intervention period and control period.

Control intervention; Experimental intervention

Eligibility Criteria

• Age: 18 Years+
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Pregnant women over age of 18
• according to each group: BMI: 18,5-24,9; BMI: \>25; women with GDM.

You may not qualify if:

• women with a physical disability that affects their movement will be excluded from the study

Sponsors & Collaborators

• University of Aarhus: lead

Study Sites (1)

Department of Obstetrics and Gynecology, Aarhus University Hospital

Aarhus, 8200, Denmark

Location

Related Publications (1)

• Andersen MB, Fuglsang J, Ostenfeld EB, Poulsen CW, Daugaard M, Ovesen PG. Postprandial interval walking-effect on blood glucose in pregnant women with gestational diabetes. Am J Obstet Gynecol MFM. 2021 Nov;3(6):100440. doi: 10.1016/j.ajogmf.2021.100440. Epub 2021 Jun 30.

  PMID: 34216833 DERIVED

MeSH Terms

Conditions

Diabetes, Gestational

Interventions

Exercise

Condition Hierarchy (Ancestors)

Pregnancy Complications; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Diabetes Mellitus; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Per Ovesen, MD, Prof.

  Aarhus University Hospital / University of Aarhus

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 9, 2018
• First Posted: August 21, 2018
• Study Start: April 3, 2018
• Primary Completion: January 31, 2021
• Study Completion: January 31, 2021
• Last Updated: April 21, 2021

Record last verified: 2021-01

Data Sharing

• IPD Sharing: Will not share

Locations

DK (1)