Does Exercise Timing Affect Glucose Levels in People With Diabetes?
1 other identifier
interventional
14
1 country
1
Brief Summary
It is not clear if there is an optimal time for exercise to improve blood glucose profiles in people with type 2 diabetes. The goal of this study is to compare post meal and 24-hour glucose levels in 4 different conditions: i-seated control, ii-fasted state exercise, iii-30 minutes post meal exercise, and iv- 3-4-hour post meal exercise. The primary outcome of this study is glucose control assessed over 24 hours using continuous glucose monitoring.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable type-2-diabetes-mellitus
Started Jun 2018
Shorter than P25 for not_applicable type-2-diabetes-mellitus
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 1, 2018
CompletedFirst Submitted
Initial submission to the registry
July 9, 2018
CompletedFirst Posted
Study publicly available on registry
August 10, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2019
CompletedSeptember 26, 2019
September 1, 2019
9 months
July 9, 2018
September 24, 2019
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Mean 24-hour glucose
Glucose measured by continuous glucose monitoring over 24 hours starting at the beginning of exercise on seated control
Within the 24 hours following exercise or control
Secondary Outcomes (5)
Postprandial glucose
Within the 24 hours following exercise or control
Glucose variability
Within the 24 hours following exercise or control
Fasting glucose
Within the 24 hours following exercise or control
Energy expenditure (METs)
Within the 50 minutes of exercise or control
Respiratory Exchange Ratio (RER)
Within the 50 minutes of exercise or control
Study Arms (4)
Seated Control
EXPERIMENTALMorning Exercise (walking)
EXPERIMENTALAfternoon Exercise (walking)
EXPERIMENTALEvening Exercise (walking)
EXPERIMENTALInterventions
Walking will last 50 minutes and will be at 5.0 km/h and at 0.5% incline
Participants will be asked to sit quietly and read during a 50 minute control period
Eligibility Criteria
You may qualify if:
- Diagnosed with T2D for more than 6 months
- years of age
- Able to understand English or French and comply with study requirements (e.g., attend visits during the day)
You may not qualify if:
- Contraindications to exercise (PAR-Q+, Rose Angina questionnaire, limited ability to walk for 50 min).
- Allergies or dietary restriction that could prevent adherence to standardize meals.
- Previous myocardial infarction, stroke or diagnosed coronary artery disease
- Changes in diabetes medication in last 3 months
- Treated by insulin or corticosteroids
- Change in body weight (\>5%) in last 3 months
- Blood pressure \>160/100 mmHg; resting heart rate\>100
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Alberta
Edmonton, Alberta, T6G 2E1, Canada
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Normand Boule, PhD
University of Alberta
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- SUPPORTIVE CARE
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
July 9, 2018
First Posted
August 10, 2018
Study Start
June 1, 2018
Primary Completion
March 1, 2019
Study Completion
March 1, 2019
Last Updated
September 26, 2019
Record last verified: 2019-09