NCT02136654

Brief Summary

South Asians (SA) living in Canada and globally have high rates of type 2 diabetes (diabetes). Despite the burden of diabetes in this population, diabetes management remains poor. SA patients are less likely to exercise, follow a healthy diet (4), participate in exercise programs (5), and are 24% less likely to achieve glucose, blood pressure and lipid targets for diabetes than the general population (6). 55-60% of SA patients were non-adherent to their diabetes life-saving medications, compared to 30-35% non-adherence in the general population (7). This large gap in diabetes care is not surprising given language and communication barriers between primary care providers and SA patients (8-10), lack of knowledge about diabetes (8-11), preference for alternative therapies (12-14) and fundamentally different cultural beliefs on diabetes and diabetes management (15-18). Although there is some preliminary evidence that culturally tailored, chronic disease models may improve outcomes (21-24), the current evidence base is insufficient to justify the system modifications required to provide culturally tailored care across primary care settings in Canada. We propose to conduct a randomized controlled trial to assess the impact of a novel culturally tailored lifestyle and medication adherence intervention in SA patients with poorly controlled diabetes. The study is called the Novel Model for South Asian diabetes Treatment (NaMaSTe-Diabetes) trial in primary care.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
600

participants targeted

Target at P75+ for not_applicable type-2-diabetes-mellitus

Timeline
Completed

Started Jul 2015

Longer than P75 for not_applicable type-2-diabetes-mellitus

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 29, 2014

Completed
14 days until next milestone

First Posted

Study publicly available on registry

May 13, 2014

Completed
1.1 years until next milestone

Study Start

First participant enrolled

July 1, 2015

Completed
6.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2021

Completed
Last Updated

November 27, 2020

Status Verified

November 1, 2020

Enrollment Period

6.4 years

First QC Date

April 29, 2014

Last Update Submit

November 24, 2020

Conditions

Keywords

diabetesethnicitySouth Asiandiabetes management

Outcome Measures

Primary Outcomes (1)

  • Change in A1C or blood pressure (systolic or diastolic blood pressure)

    within 6 months from baseline; 0, 3, and 6 months

Secondary Outcomes (3)

  • change in fasting lipid profile

    6 months; 0 and 6 months

  • Change in weight or waist circumference

    6 months; 0, 3, and 6 months

  • change in health status

    6 months; 0, 3, and 6 months

Other Outcomes (1)

  • Procedure related outcomes

    6 months; 0, 3, and 6 months

Study Arms (2)

Culturally tailored diabetes program

EXPERIMENTAL

Culturally tailored diabetes program * culturally tailored diabetes education * lifestyle counselling * medication adherence counseling * peer supporter * communication training * family member involvement

Behavioral: Culturally tailored diabetes program

Usual Care

NO INTERVENTION

Usual Care includes continuing to visit primary care physician for ongoing diabetes management Printed diabetes education materials.

Interventions

Includes family member and peer support Includes communication training

Culturally tailored diabetes program

Eligibility Criteria

Age19 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • age \>19 years of age
  • type 2 diabetes mellitus requiring at least one medication (oral hypoglycemic agent and/or insulin) to control diabetes
  • A1C ≥7% in past 1 year
  • willingness/ability to attend the Diabetes education, dietician, and peer sessions and follow up assessments
  • ability to provide informed consent
  • self identify as South Asian (from India, Pakistan, Sri Lanka, or Bangladesh) regardless of generational status or timing of immigration with ability to speak in English or Punjabi.

You may not qualify if:

  • life- limiting illness \<12 months
  • physical inability to exercise
  • recurrent severe hypoglycemia or hypoglycaemic unawareness
  • family member of, or living in same household as a participant
  • pregnancy or gestational diabetes.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of British Columbia

Vancouver, British Columbia, V6Z 1Y6, Canada

RECRUITING

MeSH Terms

Conditions

Diabetes Mellitus, Type 2Diabetes Mellitus

Condition Hierarchy (Ancestors)

Glucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Study Officials

  • Nadia A Khan, MD MSc

    University of British Columbia

    PRINCIPAL INVESTIGATOR
  • Tricia Tang, PhD

    University pf British Columbia

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Gurpreet Oshan, BA

CONTACT

Nadia A Khan, MD MSc

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

April 29, 2014

First Posted

May 13, 2014

Study Start

July 1, 2015

Primary Completion

December 1, 2021

Study Completion

December 1, 2021

Last Updated

November 27, 2020

Record last verified: 2020-11

Locations