Ridge Preservation In Mandibular Molars Using Mixture Of ABB And Autogenous Particulate VS Sticky Bone

NCT03584997 | Unknown DMC

• 1 other identifier: 5050
• Study Type: interventional
• Target: 20
• Locations: 0 countries
• Sites: N/A

Brief Summary

Histological Measurement Comparing the density of the new bone formed during socket preservation technique using a Mixture of Anorganic Bovine Bone(ABB) And Autogenous Particulate vs a Mixture of Injectable Platelets Rich Fibers, ABB And Autogenous Particulates (sticky bone). radiographical measurements of the amount of bone dimensions changes in socket preservation technique in 6-month period using a Mixture Of Anorganic Bovine Bone(ABB) And Autogenous Particulate vs a Mixture Of Injectable Platelets Rich Fibers, ABB And Autogenous Particulates (sticky bone)

Conditions

Alveolar Bone Loss; Bone Graft Failure; Alveolar Bone Resorption

Outcome Measures

Primary Outcomes (1)

• histomorphometrical bone quality

  histological bone quality measured from a core sample taken from the grafted site

  6 month

Secondary Outcomes (1)

• marginal bone loss

  6 month

Study Arms (2)

PRF , ABB & Autogenous Particulate

EXPERIMENTAL

Platelets rich fibrin + anorganic bovine bone + autogenous particulate graft

Procedure: PRF, ABB & Autogenous Particulate

ABB And Autogenous Particulate

ACTIVE COMPARATOR

anorganic bovine bone +autogenous particulate graft

Procedure: ABB And Autogenous Particulate

Interventions

ABB And Autogenous Particulate PROCEDURE

Mixing the autogenous bone graft aquired at the time of surgery with a 50:50 ration of anorganic bovine bone and filling the socket

ABB And Autogenous Particulate

PRF, ABB & Autogenous Particulate PROCEDURE

adding an injectable platelets rich fibrin to a Mixture of autogenous bone graft aquired at the time of surgery with a 50:50 ration of anorganic bovine bone and filling the socket

PRF , ABB & Autogenous Particulate

Eligibility Criteria

• Age: 20 Years - 50 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Adult patients with hopeless mandibular molars indicated for extraction and implant placement in two stages that indicate socket preservation.
• Both sexes.
• No intraoral soft and hard tissue pathology.
• No systemic condition that contraindicate implant placement.

You may not qualify if:

• Presence of fenestrations or dehiscence of the residual bony Walls after extraction.
• Heavy smokers more than 20 cigarettes per day .(24)
• Patients with systemic disease that may affect normal healing.
• Psychiatric problems
• Disorders to implant are related to history of radiation therapy to the head and neck neoplasia, or bone augmentation to implant site.
• Patients that refuse to be called back for implant placement post extraction.
• Patients that have exceeded bone resorption surrounding the tooth prior to extraction and require guided bone regeneration.

Sponsors & Collaborators

• Cairo University: lead

MeSH Terms

Conditions

Alveolar Bone Loss

Interventions

Prolactin-Releasing Hormone

Condition Hierarchy (Ancestors)

Bone Resorption; Bone Diseases; Musculoskeletal Diseases; Periodontal Atrophy; Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases

Intervention Hierarchy (Ancestors)

Hypothalamic Hormones; Peptide Hormones; Hormones; Hormones, Hormone Substitutes, and Hormone Antagonists; Neuropeptides; Peptides; Amino Acids, Peptides, and Proteins; Nerve Tissue Proteins; Proteins

Central Study Contacts

Mohammed D Darwish, Masters

CONTACT

00201206036565; doctorelsayed87@hotmail.com

Mohammed D Darwish, Masters

CONTACT

00201206036365; doctorelsayed87@hotmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: QUADRUPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: June 29, 2018
• First Posted: July 12, 2018
• Study Start: August 1, 2018
• Primary Completion: December 1, 2018
• Study Completion: July 1, 2019
• Last Updated: July 17, 2018

Record last verified: 2018-07