NCT03566264

Brief Summary

An observational study using data from a large US electronic health record database to find participants hospitalized with ADHF who do not have a concurring heart attack

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Aug 2017

Typical duration for all trials

Geographic Reach
1 country

2 active sites

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 22, 2017

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

April 24, 2018

Completed
2 months until next milestone

First Posted

Study publicly available on registry

June 25, 2018

Completed
2.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 15, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 15, 2020

Completed
Last Updated

July 8, 2022

Status Verified

July 1, 2022

Enrollment Period

3.3 years

First QC Date

April 24, 2018

Last Update Submit

July 6, 2022

Conditions

Outcome Measures

Primary Outcomes (4)

  • Incidence of comorbid events among hospitalized ADHF participants

    In the 30 days after discharge

  • Incidence of participants hospitalized with ADHF

    Up to 66 months

  • Incidence of participants hospitalized with ADHF

    In the 30 days after discharge

  • Incidence of comorbid events among hospitalized ADHF participants

    Up to 66 months

Study Arms (1)

Participants hospitalized with ADHF

Other: Non-Interventional

Interventions

Non-Interventional

Participants hospitalized with ADHF

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Study population will be participants hospitalized with ADHF who do not have a coincident myocardial infarction and who have at least 6 months of activity in the database prior to the hospitalization

You may qualify if:

  • Age 18 years or older on the index date
  • At least 6 months of activity in the database
  • An inpatient visit with at least one of the following ICD-9 or ICD-10 diagnosis codes (ICD-9 diagnosis codes: 428.xx, 785.51 or ICD-10 diagnosis codes: I50.xx, R57.0) in the primary or secondary position OR mention of "heart failure" on the admission record

You may not qualify if:

  • An average LVEF ≥ 40 during the hospitalization
  • Any code for myocardial infarction (ICD-9 diagnosis code: 410.xx, ICD-10 diagnosis code: I21.xx) or related terms such as "myocardial infarction", "mi", "infarct" or "heart attack" occurring during the index hospitalization

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Bristol-Myers Squibb

Princeton, New Jersey, 08540, United States

Location

Local Institution

Princeton, New Jersey, 08540, United States

Location

Related Links

MeSH Terms

Conditions

Heart Failure

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Study Officials

  • Bristol-Myers Squibb

    Bristol-Myers Squibb

    STUDY DIRECTOR
0

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 24, 2018

First Posted

June 25, 2018

Study Start

August 22, 2017

Primary Completion

December 15, 2020

Study Completion

December 15, 2020

Last Updated

July 8, 2022

Record last verified: 2022-07

Locations