NCT02928263

Brief Summary

A retrospective study to evaluate healthcare cost and resource utilization for patients with metastatic renal cell carcinoma who have been treated with IV or oral agents

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Feb 2017

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 7, 2016

Completed
3 days until next milestone

First Posted

Study publicly available on registry

October 10, 2016

Completed
5 months until next milestone

Study Start

First participant enrolled

February 28, 2017

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 31, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2017

Completed
Last Updated

July 17, 2017

Status Verified

July 1, 2017

Enrollment Period

3 months

First QC Date

October 7, 2016

Last Update Submit

July 13, 2017

Conditions

Outcome Measures

Primary Outcomes (4)

  • Distribution of Healthcare costs for patients treated with oral drugs used in the first-line treatment of Metastatic renal cell carcinoma (mRCC)

    All-cause healthcare costs will be calculated in the first-line oral cohort as per-patient-per-month (PPPM) costs.

    Up to 63 months

  • Composite of Resource Utilization for patients treated with oral drugs used in the first-line treatment of mRCC

    Total numbers and rates of inpatient, outpatient, and emergency room visits per patient will be calculated.

    Up to 63 months

  • Distribution of Healthcare costs for patients treated with IV drugs used in the first-line treatment of mRCC

    All-cause healthcare costs will be calculated in the first-line IV cohort as per-patient-per-month (PPPM) costs.

    Up to 63 months

  • Composite of Resource Utilization for patients treated with IV drugs used in the first-line treatment of mRCC

    Total numbers and rates of inpatient, outpatient, and emergency room visits per patient will be calculated.

    Up to 63 months

Secondary Outcomes (2)

  • Medication Possession Ratio (MPR) for patients treated with oral drugs used in the first-line treatment of mRCC

    Up to 63 months

  • Medication Possession Ratio (MPR) for patients treated with IV drugs used in the first-line treatment of mRCC

    Up to 63 months

Study Arms (2)

Patients treated with IV agents

Metastatic renal cell carcinoma patients treated with IV agents

Other: Non-Interventional

Patients treated with oral agents

Metastatic renal cell carcinoma patients treated with oral agents

Other: Non-Interventional

Interventions

Other

Patients treated with IV agentsPatients treated with oral agents

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Metastatic RCC patients in the US identified from administrative claim databases

You may qualify if:

  • Diagnosis with metastatic renal cell carcinoma
  • Prescription/administration of one of the IV or oral agents examined in the study

You may not qualify if:

  • Patients with other primary cancer diagnosis before RCC diagnosis
  • Patients with pregnancy or HIV/AIDS

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bristol-Myers Squibb

Princeton, New Jersey, 08540, United States

Location

Related Links

MeSH Terms

Conditions

Carcinoma, Renal Cell

Condition Hierarchy (Ancestors)

AdenocarcinomaCarcinomaNeoplasms, Glandular and EpithelialNeoplasms by Histologic TypeNeoplasmsKidney NeoplasmsUrologic NeoplasmsUrogenital NeoplasmsNeoplasms by SiteFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesKidney DiseasesUrologic DiseasesMale Urogenital Diseases

Study Officials

  • Bristol-Myers Squibb

    Bristol-Myers Squibb

    STUDY DIRECTOR
0

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 7, 2016

First Posted

October 10, 2016

Study Start

February 28, 2017

Primary Completion

May 31, 2017

Study Completion

May 31, 2017

Last Updated

July 17, 2017

Record last verified: 2017-07

Locations