Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 50/100

Failure Rate

14.7%

418 terminated/withdrawn out of 2846 trials

Success Rate

81.8%

-4.7% vs industry average

Late-Stage Pipeline

19%

539 trials in Phase 3/4

Results Transparency

48%

900 of 1885 completed trials have results

Key Signals

186 recruiting900 with results302 terminated116 withdrawn

Enrollment Performance

Analytics

Phase 1
911(37.9%)
Phase 2
843(35.1%)
Phase 3
390(16.2%)
Phase 4
149(6.2%)
N/A
93(3.9%)
Early Phase 1
19(0.8%)
2405Total
Phase 1(911)
Phase 2(843)
Phase 3(390)
Phase 4(149)
+2 more

Activity Timeline

Global Presence

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Clinical Trials (2846)

Showing 20 of 2846 trials
NCT03681561Phase 1Recruiting

Nivolumab With Ruxolitinib in Relapsed or Refractory Classical Hodgkin Lymphoma

Role: collaborator

NCT03104439Phase 2Active Not Recruiting

Nivolumab and Ipilimumab and Radiation Therapy in MSS and MSI High Colorectal and Pancreatic Cancer

Role: collaborator

NCT07248839Phase 1Recruiting

A Study to Assess the Drug Levels and Safety of BMS-986435 in Participants With Normal Hepatic Function and Participants With Different Degrees of Hepatic Impairment

Role: lead

NCT06549608Completed

A Retrospective Cohort Study of Mavacamten Patient Support Program in Canada

Role: lead

NCT05489705Recruiting

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

Role: lead

NCT07061288Phase 1Recruiting

A Study to Evaluate the Safety, Tolerability, and PK of an Injectable Form of KarXT

Role: lead

NCT04658147Phase 1Active Not Recruiting

Feasibility and Efficacy of Perioperative Nivolumab With or Without Relatlimab for Patients With Potentially Resectable Hepatocellular Carcinoma (HCC)

Role: collaborator

NCT05076175Phase 2Recruiting

A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

Role: lead

NCT06869551Phase 3Recruiting

A Study to Evaluate the Drug Levels, Efficacy, and Safety of Deucravacitinib (BMS-986165) in Pediatric Participants With Juvenile Psoriatic Arthritis

Role: lead

NCT07175285Recruiting

A Study in Participants With Active Systemic Lupus Erythematosus With Inadequate Response to Glucocorticoids and ≥2 Immunosuppressants

Role: lead

NCT04290546Phase 1Completed

CIML NK Cell in Head & Neck Cancer

Role: collaborator

NCT07011745Phase 3Recruiting

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-2)

Role: lead

NCT07508488Phase 2Recruiting

Deucravacitinib in the Treatment of Cicatricial Alopecias

Role: collaborator

NCT06926868Phase 2Recruiting

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Role: lead

NCT06215118Phase 1Recruiting

A Study to Learn About the Effects of the Combination of Elranatamab (PF-06863135) and Iberdomide in Patients With Relapsed or Refractory Multiple Myeloma (MagnetisMM-30)

Role: collaborator

NCT06855771Phase 2Recruiting

A Study of Navlimetostat (BMS-986504) in Participants With Pre-treated Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) With Homozygous MTAP Deletion (MountainTAP-9)

Role: lead

NCT03557359Phase 2Completed

Nivolumab for Recurrent or Progressive IDH Mutant Gliomas

Role: collaborator

NCT07011732Phase 3Recruiting

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)

Role: lead

NCT07140913Phase 3Recruiting

A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine

Role: lead

NCT04879368Phase 3Completed

RegoNivo vs Standard of Care Chemotherapy in AGOC

Role: collaborator